AntibioticMech

secnidazole

CHEBI:140628 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 2-hydroxypropyl and methyl groups, respectively. It is a drug used for the treatment of trichomoniasis caused by Trichomonas vaginalis. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:24780 CHEBI:24780
• CHEBI:35681 CHEBI:35681
• CHEBI:35716 CHEBI:35716

Chemical structure

Computed structure properties

Molecular formula	C7H11N3O3
Charge	0
Average mass	185.183 Da
Monoisotopic mass	185.08004 Da
Source	ChEBI
InChIKey	KPQZUUQMTUIKBP-UHFFFAOYSA-N

SMILES

Cc1ncc([N+](=O)[O-])n1CC(C)O

InChI

InChI=1S/C7H11N3O3/c1-5(11)4-9-6(2)8-3-7(9)10(12)13/h3,5,11H,4H2,1-2H3

Also called

• Flagentyl (BRAND_NAME)— chebi
• Secnidal (BRAND_NAME)— chebi
• Solosec (BRAND_NAME)— chebi
• secnidazol (INN)— chebi
• secnidazolum (INN)— chebi
• 1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol (EXACT_SYNONYM)— chebi
• 1-(2-methyl-5-nitro-1-imidazolyl)-2-propanol (EXACT_SYNONYM)— chebi
• PM-185184 (EXACT_SYNONYM)— chebi
• RP 14539 (EXACT_SYNONYM)— chebi
• RP-14539 (EXACT_SYNONYM)— chebi
• SYM-1219 (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:3366-95-8
• drugbank:DB12834
• drugcentral:2427
• hmdb:HMDB0258202
• kegg.drug:D07353
• lincs.smallmolecule:LSM-5131
• patent:US4920141
• patent:US4925951
• patent:US4925952
• patent:US4957918
• patent:US5549911
• reaxys:612717
• wikipedia.en:Secnidazole

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33282 CHEBI:33282
• CHEBI:35820 CHEBI:35820

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:140628	secnidazole	antibioticmech:chebi-3f161bf2e3	2026-08-30

Mechanism summary

Clinical status

APPROVED

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

5. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.