sulfathiourea

CHEBI:131723 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A substituted aniline that is thiourea in which one of the hydrogens has been replaced by a (p-aminophenyl)sulfonyl group. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:48975
Label unavailable CHEBI:51276
sulfonamide antibiotic CHEBI:87228

Chemical structure

Computed structure properties
Molecular formula	C7H9N3O2S2
Charge	0
Average mass	231.302 Da
Monoisotopic mass	231.01362 Da
Source	ChEBI
InChIKey	UEMLYRZWLVXWRU-UHFFFAOYSA-N

SMILES

NC(=S)NS(=O)(=O)c1ccc(N)cc1

InChI

InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)

Also called

Badional (BRAND_NAME)— chebi
Fontamide (BRAND_NAME)— chebi
sulfathiourée (INN)— chebi
sulfatiourea (INN)— chebi
4-amino-N-carbamothioylbenzenesulfonamide (EXACT_SYNONYM)— chebi
1-sulfanilyl-2-thiourea (EXACT_SYNONYM)— chebi
2-Sulfanilamidothiokarbamid (EXACT_SYNONYM)— chebi
4-amino-N-(aminothioxomethyl)benzenesulfonamide (EXACT_SYNONYM)— chebi
R.P. 2255 (EXACT_SYNONYM)— chebi
RP 2255 (EXACT_SYNONYM)— chebi
RP-2255 (EXACT_SYNONYM)— chebi
p-aminobenzenesulfonylthiourea (EXACT_SYNONYM)— chebi
p-aminophenylsulfonylthiourea (EXACT_SYNONYM)— chebi
sulfathiocarbamide (EXACT_SYNONYM)— chebi
sulphathiourea (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

cas:515-49-1
reaxys:2696478

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antimicrobial agent CHEBI:33281
antibacterial drug CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:131723`	sulfathiourea	`antibioticmech:chebi-e09b064ba5`	2026-08-30

Mechanism summary

Mode of action: FOLATE_PATHWAY_INHIBITION microbial target — Assigned from ChEBI role CHEBI:50502 (EC 2.5.1.15 (dihydropteroate synthase) inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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