sulfathiourea

CHEBI:131723 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A substituted aniline that is thiourea in which one of the hydrogens has been replaced by a (p-aminophenyl)sulfonyl group. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:48975 CHEBI:48975
CHEBI:51276 CHEBI:51276
CHEBI:87228 CHEBI:87228

Chemical structure

Computed structure properties
Molecular formula	C7H9N3O2S2
Charge	0
Average mass	231.302 Da
Monoisotopic mass	231.01362 Da
Source	ChEBI
InChIKey	UEMLYRZWLVXWRU-UHFFFAOYSA-N

SMILES

NC(=S)NS(=O)(=O)c1ccc(N)cc1

InChI

InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)

Also called

Badional (BRAND_NAME)— chebi
Fontamide (BRAND_NAME)— chebi
sulfathiourée (INN)— chebi
sulfatiourea (INN)— chebi
4-amino-N-carbamothioylbenzenesulfonamide (EXACT_SYNONYM)— chebi
1-sulfanilyl-2-thiourea (EXACT_SYNONYM)— chebi
2-Sulfanilamidothiokarbamid (EXACT_SYNONYM)— chebi
4-amino-N-(aminothioxomethyl)benzenesulfonamide (EXACT_SYNONYM)— chebi
R.P. 2255 (EXACT_SYNONYM)— chebi
RP 2255 (EXACT_SYNONYM)— chebi
RP-2255 (EXACT_SYNONYM)— chebi
p-aminobenzenesulfonylthiourea (EXACT_SYNONYM)— chebi
p-aminophenylsulfonylthiourea (EXACT_SYNONYM)— chebi
sulfathiocarbamide (EXACT_SYNONYM)— chebi
sulphathiourea (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:515-49-1
drugcentral:3567
kegg.drug:D07239
patent:US2332906
reaxys:2696478
wikipedia.en:Sulfathiourea

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281
CHEBI:36047 CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:131723`	sulfathiourea	`antibioticmech:chebi-e09b064ba5`	2026-08-30

Mechanism summary

Mode of action: FOLATE_PATHWAY_INHIBITION microbial target — Assigned from ChEBI role CHEBI:50502 (EC 2.5.1.15 (dihydropteroate synthase) inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.