thioacetazone

CHEBI:134958 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

Thioacetazone is an inexpensive, antitubercular, bacteriostatic drug that has been widely used in combination with isoniazid in Africa and South America. This drug is rarely in use. — PMID:18094751

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

thiosemicarbazone antibioticARO:3007161

Strictly broader compounds or drug classes this molecule belongs to.

ARO:3007161 ARO:3007161

Chemical structure

Computed structure properties
Molecular formula	C10H12N4OS
Charge	0
Average mass	236.3 Da
Monoisotopic mass	236.07318 Da
Source	ChEBI
InChIKey	SRVJKTDHMYAMHA-UHFFFAOYSA-N

SMILES

CC(=O)Nc1ccc(C=NNC(N)=S)cc1

InChI

InChI=1S/C10H12N4OS/c1-7(15)13-9-4-2-8(3-5-9)6-12-14-10(11)16/h2-6H,1H3,(H,13,15)(H3,11,14,16)

Also called

amithiozone (EXACT_SYNONYM)— aro
thiacetazone (EXACT_SYNONYM)— aro

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3004952`	thioacetazone	`antibioticmech:aro-727d7249f2`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.