AntibioticMech

tinidazole

CHEBI:63627 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent. — ChEBI

Classification

nitroimidazole antibioticARO:3004115

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:24780 CHEBI:24780
• ARO:3004115 ARO:3004115

Chemical structure

Computed structure properties

Molecular formula	C8H13N3O4S
Charge	0
Average mass	247.276 Da
Monoisotopic mass	247.06268 Da
Source	ChEBI
InChIKey	HJLSLZFTEKNLFI-UHFFFAOYSA-N

SMILES

CCS(=O)(=O)CCn1c([N+](=O)[O-])cnc1C

InChI

InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3

Also called

• 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole (EXACT_SYNONYM)— chebi
• timidazole (EXACT_SYNONYM)— chebi
• Fasigyn (EXACT_SYNONYM)— aro
• Simplotan (EXACT_SYNONYM)— aro
• Sporinex (EXACT_SYNONYM)— aro
• Tindamax (EXACT_SYNONYM)— aro

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3004026
• drugbank:DB00911
• drugcentral:2671
• kegg.drug:D01426
• lincs.smallmolecule:LSM-5948
• patent:US3376311
• reaxys:618182
• wikipedia.en:Tinidazole
• chembl:CHEMBL1220
• pubchem.compound:5479

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35820 CHEBI:35820
• CHEBI:36047 CHEBI:36047

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3004026	tinidazole	antibioticmech:aro-8f1695644d	2026-08-30
CHEBI	CHEBI:63627	tinidazole	antibioticmech:chebi-1a293bfc81	2026-08-30

Mechanism summary

Clinical status

APPROVED

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

5. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.