AntibioticMech

tirapazamine

CHEBI:78887 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

A member of the class of benzotriazines that is 1,2,4-benzotriazine carrying an amino substituent at position 3 and two oxido substituents at positions 1 and 4. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:33860 CHEBI:33860
• CHEBI:35580 CHEBI:35580
• CHEBI:51361 CHEBI:51361

Chemical structure

Computed structure properties

Molecular formula	C7H6N4O2
Charge	0
Average mass	178.151 Da
Monoisotopic mass	178.04908 Da
Source	ChEBI
InChIKey	ORYDPOVDJJZGHQ-UHFFFAOYSA-N

SMILES

Nc1n[n+]([O-])c2ccccc2[n+]1[O-]

InChI

InChI=1S/C7H6N4O2/c8-7-9-11(13)6-4-2-1-3-5(6)10(7)12/h1-4H,(H2,8,9)

Also called

• 1,2,4-benzotriazin-3-amine 1,4-dioxide (EXACT_SYNONYM)— chebi
• 3-Amino-1,2,4-benzotriazine 1,4-dioxide (EXACT_SYNONYM)— chebi
• SR 4233 (EXACT_SYNONYM)— chebi
• SR-4233 (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:27314-97-2
• kegg.drug:D06167
• reaxys:179322
• wikipedia.en:Tirapazamine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:78887	tirapazamine	antibioticmech:chebi-59e131c858	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.