tuberactinomycin
antibioticmech:aro-4c6e0c1ff0
·ANTIBACTERIAL
·MINTED
SEEDED
Tuberactinomycins are a family of cyclic peptide antibiotics that are important in the treatment of tuberculosis. Tuberactinomycins contain nonproteinogenic amino acids and inhibit group I self-splicing RNA to disrupt prokaryotic protein synthesis. — PMID:7509881
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
nonribosomal peptide antibioticsARO:3009657
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C25H43N13O11 |
|---|
| Charge | 0 |
|---|
| Average mass | 701.7 Da |
|---|
| Monoisotopic mass | 701.32049924 Da |
|---|
| Source | PubChem · retrieved 2026-08-29 |
|---|
| InChIKey | JCTPGOAHEVLZAB-KIXAZQDESA-N |
|---|
SMILES
C1[C@@H](NC(=N[C@H]1O)N)C2C(=O)NCC(C(=O)NC(C(=O)NC(C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CO)CO)NC(=O)CC(C(CCN)O)N
InChI
InChI=1S/C25H43N13O11/c26-2-1-15(41)9(27)3-16(42)32-11-5-30-23(48)18(10-4-17(43)37-24(28)36-10)38-20(45)12(6-31-25(29)49)33-21(46)13(7-39)35-22(47)14(8-40)34-19(11)44/h6,9-11,13-15,17-18,39-41,43H,1-5,7-8,26-27H2,(H,30,48)(H,32,42)(H,33,46)(H,34,44)(H,35,47)(H,38,45)(H3,28,36,37)(H3,29,31,49)/b12-6-/t9?,10-,11?,13?,14?,15?,17+,18?/m1/s1
Cross-references
Equivalent identifiers for this same structure in other resources.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| ARO |
ARO:3000490 |
tuberactinomycin |
antibioticmech:aro-4c6e0c1ff0 |
2026-08-30 |
Molecular targets
The molecular entity or process this compound acts on. Each target
carries evidence — this is a mechanistic claim, not a classification.
ribosomal complex PROTEIN_COMPLEX DIRECT_BINDING_TARGET
ARO:3000729
CARD/ARO database assertion; target organism, strain, and assay are not specified. ARO asserts stabilization of the ribosomal complex by antibiotics. Evidence status: PRIMARY_EVIDENCE_NEEDED. Source: CARD_ARO 2026-08-30 (retrieved 2026-08-30).
- ARO:3000729 (CARD/ARO asserts targeted_by_antibiotic ARO:3000490 (tuberactinomycin); database assertion, not a primary citation.)
RNA guanosine binding site NUCLEIC_ACID DIRECT_BINDING_TARGET
ARO:3000739
CARD/ARO database assertion; target organism, strain, and assay are not specified. ARO asserts competition at the RNA guanosine-binding site. Evidence status: PRIMARY_EVIDENCE_NEEDED. Source: CARD_ARO 2026-08-30 (retrieved 2026-08-30).
- ARO:3000739 (CARD/ARO asserts targeted_by_antibiotic ARO:3000490 (tuberactinomycin); database assertion, not a primary citation.)
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.