AntibioticMech

UCS1025 A

CHEBI:66338 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

An organic heterotricyclic compound that incorporates a lactam and a γ-lactone as part of the cyclic system which in turn is attached to a (2,4a,8a-trimethyl-octahydronaphthalen-1-yl)carbonyl group at position 7. It is isolated from Acremonium sp. KY4917 and exhibits antibacterial activity. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:138397 CHEBI:138397
• CHEBI:17087 CHEBI:17087
• CHEBI:24995 CHEBI:24995
• CHEBI:26878 CHEBI:26878
• CHEBI:26979 CHEBI:26979
• CHEBI:37581 CHEBI:37581

Chemical structure

Computed structure properties

Molecular formula	C22H29NO5
Charge	0
Average mass	387.476 Da
Monoisotopic mass	387.20457 Da
Source	ChEBI
InChIKey	WOAILDKFDXKSIY-OMKDVXPQSA-N

SMILES

[H][C@@]1(C(=O)[C@H]2[C@@H](C)C=C[C@@]3(C)CCCC[C@]23C)C(=O)N2CC[C@@]3([H])C(=O)O[C@]1([H])[C@@]23O

InChI

InChI=1S/C22H29NO5/c1-12-6-10-20(2)8-4-5-9-21(20,3)15(12)16(24)14-17-22(27)13(19(26)28-17)7-11-23(22)18(14)25/h6,10,12-15,17,27H,4-5,7-9,11H2,1-3H3/t12-,13-,14-,15+,17-,20+,21+,22+/m0/s1

Also called

• (2aR,7R,7aS,7bR)-7b-hydroxy-7-{[(1S,2S,4aR,8aR)-2,4a,8a-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]carbonyl}hexahydrofuro[2,3,4-gh]pyrrolizine-2,6-dione (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• patent:EP1227097
• patent:US6869971
• patent:WO0129043

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:33281 CHEBI:33281
• CHEBI:33282 CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:66338	UCS1025 A	antibioticmech:chebi-8dab89f5bc	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.