valnemulin

CHEBI:29705 ·resolve ·ANTIBACTERIAL ·EXACT SEEDED

Two semi-synthetic pleuromutilin derivatives, tiamulin and valnemulin, have been developed as antibiotics for veterinary use. — PMID:22070694

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

pleuromutilin antibioticARO:3000670

Strictly broader compounds or drug classes this molecule belongs to.

pleuromutilin antibiotic ARO:3000670

Chemical structure

Computed structure properties
Molecular formula	C31H52N2O5S
Charge	0
Average mass	564.833 Da
Monoisotopic mass	564.35969 Da
Source	ChEBI
InChIKey	LLYYNOVSVPBRGV-NFQTWZMKSA-N

SMILES

[H][C@@]12C(=O)CC[C@]13CCC(C)[C@@]2(C)[C@H](OC(=O)CSC(C)(C)CNC(=O)C(N)C(C)C)C[C@@](C)(C=C)[C@@H](O)[C@@H]3C

InChI

InChI=1S/C31H52N2O5S/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37)/t19?,20-,22+,24?,25-,26-,29+,30-,31-/m0/s1

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3001315`	valnemulin	`antibioticmech:aro-f2d5bd16ef`	2026-08-30

Resistance mechanisms

2 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

ANTIBIOTIC_TARGET_PROTECTION 2

ANTIBIOTIC_TARGET_PROTECTION
Determinant	ARO ID	Organism	Gene families	Evidence
vga(E) Staphylococcus cohnii	ARO:3004715	not organism-specific	—	ARO:3004715 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001315 (valnemulin); database assertion, not a primary citation.)
vgaC	ARO:3002831	not organism-specific	—	ARO:3002831 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3001315 (valnemulin); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (valnemulin) · CultureMech · NaturalProductMech · PathwayMech · TraitMech