Visomitin

antibioticmech:curator-96ae7dffd3 ·ANTIBACTERIAL ·MINTED PROPOSED

A plastoquinonyl-decyl-triphenylphosphonium bromide with antibacterial activity against Enterococcus. — DOI:10.11817/j.issn.1672-7347.2026.250522

Chemical structure

Computed structure properties
Molecular formula	C36H42BrO2P
Charge	0
Average mass	617.6 Da
Monoisotopic mass	616.21058 Da
Source	https://pubchem.ncbi.nlm.nih.gov/compound/16679091 · retrieved 2026-09-08
InChIKey	WYHFWTRUGAFNKW-UHFFFAOYSA-M

SMILES

CC1=C(C(=O)C(=CC1=O)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

InChI

InChI=1S/C36H42O2P.BrH/c1-29-30(2)36(38)31(28-35(29)37)20-12-7-5-3-4-6-8-19-27-39(32-21-13-9-14-22-32,33-23-15-10-16-24-33)34-25-17-11-18-26-34;/h9-11,13-18,21-26,28H,3-8,12,19-20,27H2,1-2H3;1H/q+1;/p-1

Also called

SKQ1 bromide (EXACT_SYNONYM)— curator
SKQ-1 bromide (EXACT_SYNONYM)— curator
plastoquinonyl-decyl-triphenylphosphonium bromide (EXACT_SYNONYM)— curator

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

pubchem.compound:16679091

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antibacterial agent CHEBI:33282

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version	Evidence
CURATOR	`DOI:10.11817/j.issn.1672-7347.2026.250522#visomitin`	Visomitin	`antibioticmech:curator-96ae7dffd3`	2026-09-08	DOI:10.11817/j.issn.1672-7347.2026.250522 — "Yang et al. reported that Visomitin had MIC values of 4 to 8 ug/mL and MBC values of 4 to 16 ug/mL against Enterococcus, showed time-dependent bactericidal activity, inhibited and partly eradicated biofilms, and reduced abscess size and bacterial load in a mouse subcutaneous abscess model." (PubChem CID 16679091 supplies the standard InChI, InChIKey, formula, and SMILES for Visomitin.)

Curation history

PROPOSED_FROM_CURATOR_INVENTORY 2026-09-08 · seed_from_sources
Proposed from curation/curator_antibiotics.tsv

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (Visomitin) · CultureMech · NaturalProductMech · PathwayMech · TraitMech