A fluoroquinolone with potent activity against Gram-positive pathogens. Showed the most potent in vitro and in vivo activities against drug-resistant Streptococcus pneumoniae. One of the most potent antibacterial agent against penicillin-resistant S. pneumoniae in a murine systemic infection model.
Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.
fluoroquinolone antibioticARO:0000001
ARO:0000001| Molecular formula | C19H20FN5O4 |
|---|---|
| Charge | 0 |
| Average mass | 401.4 Da |
| Monoisotopic mass | 401.1499323 Da |
| Source | PubChem · retrieved 2026-08-29 |
| InChIKey | ZNPOCLHDJCAZAH-UHFFFAOYSA-N |
CON=C1CN(CC12CNC2)C3=C(C=C4C(=O)C(=CN(C4=N3)C5CC5)C(=O)O)F
InChI=1S/C19H20FN5O4/c1-29-23-14-6-24(9-19(14)7-21-8-19)17-13(20)4-11-15(26)12(18(27)28)5-25(10-2-3-10)16(11)22-17/h4-5,10,21H,2-3,6-9H2,1H3,(H,27,28)
| Source | Native ID | Label | Minted CURIE | Version |
|---|---|---|---|---|
| ARO | ARO:3004731 |
zabofloxacin | antibioticmech:aro-f75c158ac2 |
2026-08-30 |
Seeded from data/raw/ inventories (ARO)
Re-seeded from updated data/raw/ inventories
Re-seeded from updated data/raw/ inventories