AntibioticMech

5-hydroxybenzofuran-2-one

CHEBI:141343 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of 1-benzofurans that is 1-benzofuran-2(3H)-one substituted by a hydroxy group at position 5. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:33854 CHEBI:33854
• CHEBI:38830 CHEBI:38830

Chemical structure

Computed structure properties

Molecular formula	C8H6O3
Charge	0
Average mass	150.133 Da
Monoisotopic mass	150.03169 Da
Source	ChEBI
InChIKey	POUITAHNNRJWMA-UHFFFAOYSA-N

SMILES

O=C1Cc2cc(O)ccc2O1

InChI

InChI=1S/C8H6O3/c9-6-1-2-7-5(3-6)4-8(10)11-7/h1-3,9H,4H2

Also called

• 5-hydroxy-1-benzofuran-2(3H)-one (EXACT_SYNONYM)— chebi
• 2,3-dihydro-5-hydroxybenzofuran-2-one (EXACT_SYNONYM)— chebi
• 5-hydroxy-2(3H)-benzofuranone (EXACT_SYNONYM)— chebi
• 5-hydroxy-2-coumaranone (EXACT_SYNONYM)— chebi
• homogentisic acid γ-lactone (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:2688-48-4
• reaxys:128621

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:141343	5-hydroxybenzofuran-2-one	antibioticmech:chebi-a18737c543	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.