AntibioticMech

albendazole

CHEBI:16664 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations. — ChEBI

Classification

albendazole-like antibioticARO:3007163

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:22715 CHEBI:22715
• CHEBI:23003 CHEBI:23003
• CHEBI:35683 CHEBI:35683
• CHEBI:87064 CHEBI:87064
• ARO:3007163 ARO:3007163

Chemical structure

Computed structure properties

Molecular formula	C12H15N3O2S
Charge	0
Average mass	265.338 Da
Monoisotopic mass	265.0885 Da
Source	ChEBI
InChIKey	HXHWSAZORRCQMX-UHFFFAOYSA-N

SMILES

CCCSc1ccc2nc(NC(=O)OC)nc2c1

InChI

InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

Also called

• methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate (EXACT_SYNONYM)— chebi
• (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester (EXACT_SYNONYM)— chebi
• 5-(propylthio)-2-carbomethoxyaminobenzimidazole (EXACT_SYNONYM)— chebi
• Albendazole (EXACT_SYNONYM)— chebi
• Albenza (EXACT_SYNONYM)— chebi
• Eskazole (EXACT_SYNONYM)— chebi
• O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate (EXACT_SYNONYM)— chebi
• Proftril (EXACT_SYNONYM)— chebi
• Valbazen (EXACT_SYNONYM)— chebi
• Zentel (EXACT_SYNONYM)— chebi
• Albendazol (EXACT_SYNONYM)— aro
• Albendazolum (EXACT_SYNONYM)— aro
• Bilutac (EXACT_SYNONYM)— aro

Cross-references

Equivalent identifiers for this same structure in other resources.

• ARO:3007090
• cas:54965-21-8
• drugbank:DB00518
• drugcentral:103
• hmdb:HMDB0014659
• kegg.compound:C01779
• kegg.drug:D00134
• lincs.smallmolecule:LSM-3782
• metacyc.compound:ALBENDAZOLE
• pesticides:albendazole
• reaxys:752696
• vsdb:895
• wikipedia.en:Albendazole
• chembl:CHEMBL1483
• pubchem.compound:2082

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:24127 CHEBI:24127

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
ARO	ARO:3007090	albendazole	antibioticmech:aro-159648d847	2026-08-30
CHEBI	CHEBI:16664	albendazole	antibioticmech:chebi-1bab1bfd8d	2026-08-30

Mechanism summary

Clinical status

APPROVED

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

5. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.