albendazole

CHEBI:16664 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

albendazole-like antibioticARO:3007163

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:22715
Label unavailable CHEBI:23003
Label unavailable CHEBI:35683
benzimidazolylcarbamate fungicide CHEBI:87064
albendazole-like antibiotic ARO:3007163

Chemical structure

Computed structure properties
Molecular formula	C12H15N3O2S
Charge	0
Average mass	265.338 Da
Monoisotopic mass	265.0885 Da
Source	ChEBI
InChIKey	HXHWSAZORRCQMX-UHFFFAOYSA-N

SMILES

CCCSc1ccc2nc(NC(=O)OC)nc2c1

InChI

InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

Also called

methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate (EXACT_SYNONYM)— chebi
(5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester (EXACT_SYNONYM)— chebi
5-(propylthio)-2-carbomethoxyaminobenzimidazole (EXACT_SYNONYM)— chebi
Albendazole (EXACT_SYNONYM)— chebi
Albenza (EXACT_SYNONYM)— chebi
Eskazole (EXACT_SYNONYM)— chebi
O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate (EXACT_SYNONYM)— chebi
Proftril (EXACT_SYNONYM)— chebi
Valbazen (EXACT_SYNONYM)— chebi
Zentel (EXACT_SYNONYM)— chebi
Albendazol (EXACT_SYNONYM)— aro
Albendazolum (EXACT_SYNONYM)— aro
Bilutac (EXACT_SYNONYM)— aro

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

wikipedia.en:Albendazole

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

fungicide CHEBI:24127

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3007090`	albendazole	`antibioticmech:aro-159648d847`	2026-08-30
CHEBI	`CHEBI:16664`	albendazole	`antibioticmech:chebi-1bab1bfd8d`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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