benomyl

CHEBI:3015 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

benzimidazole antifungalARO:3009317

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:22715
Label unavailable CHEBI:23003
Label unavailable CHEBI:62733
benzimidazole fungicide CHEBI:87036
benzimidazolylcarbamate fungicide CHEBI:87064
benzimidazole antifungal ARO:3009317

Chemical structure

Computed structure properties
Molecular formula	C14H18N4O3
Charge	0
Average mass	290.323 Da
Monoisotopic mass	290.13789 Da
Source	ChEBI
InChIKey	RIOXQFHNBCKOKP-UHFFFAOYSA-N

SMILES

CCCCNC(=O)n1c(NC(=O)OC)nc2ccccc21

InChI

InChI=1S/C14H18N4O3/c1-3-4-9-15-13(19)18-11-8-6-5-7-10(11)16-12(18)17-14(20)21-2/h5-8H,3-4,9H2,1-2H3,(H,15,19)(H,16,17,20)

Also called

methyl [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamate (EXACT_SYNONYM)— chebi
1-(Butylcarbamoyl)-2-benzimidazol-methylcarbamat (EXACT_SYNONYM)— chebi
1-(Butylcarbamoyl)-2-benzimidazolecarbamic acid, methyl ester (EXACT_SYNONYM)— chebi
1-(N-Butylcarbamoyl)-2-(methoxy-carboxamido)-benzimidazol (EXACT_SYNONYM)— chebi
Benlate (EXACT_SYNONYM)— chebi
Benomyl (EXACT_SYNONYM)— chebi
Methyl 1-(butylamino)carbonyl-1H-benzimidazol-2-ylcarbamate (EXACT_SYNONYM)— chebi
Methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate (EXACT_SYNONYM)— chebi
Methyl N-(1-butylcarbamoyl-2-benzimidazole)carbamate (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

wikipedia.en:Benomyl

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

fungicide CHEBI:24127
antifungal agrochemical CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009161`	benomyl	`antibioticmech:aro-bedb50e028`	2026-08-30
CHEBI	`CHEBI:3015`	benomyl	`antibioticmech:chebi-b4bae81658`	2026-08-30

Resistance mechanisms

2 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

ANTIBIOTIC_TARGET_ALTERATION 2

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Aspergillus fumigatus beta-tubulin with mutations conferring resistance to benomyl	ARO:3009478	not organism-specific	—	ARO:3009478 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009161 (benomyl); database assertion, not a primary citation.)
Colletotrichum gloeosporioides beta-tubulin with mutations conferring resistance against benomyl	ARO:3009469	not organism-specific	—	ARO:3009469 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009161 (benomyl); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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