curcumin

CHEBI:3962 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A β-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26195 CHEBI:26195
CHEBI:35618 CHEBI:35618
CHEBI:51689 CHEBI:51689
CHEBI:67265 CHEBI:67265
CHEBI:78802 CHEBI:78802

Chemical structure

Computed structure properties
Molecular formula	C21H20O6
Charge	0
Average mass	368.385 Da
Monoisotopic mass	368.12599 Da
Source	ChEBI
InChIKey	VFLDPWHFBUODDF-FCXRPNKRSA-N

SMILES

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O

InChI

InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

Also called

(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione (EXACT_SYNONYM)— chebi
C.I. 75300 (EXACT_SYNONYM)— chebi
C.I. Natural Yellow 3 (EXACT_SYNONYM)— chebi
Curcumin (EXACT_SYNONYM)— chebi
Diferuloylmethane (EXACT_SYNONYM)— chebi
E 100 (EXACT_SYNONYM)— chebi
Kacha haldi (EXACT_SYNONYM)— chebi
Natural yellow 3 (EXACT_SYNONYM)— chebi
Turmeric yellow (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:458-37-7
chemspider:839564
drugbank:DB11672
hmdb:HMDB0002269
kegg.compound:C10443
knapsack:C00002731
lincs.smallmolecule:LSM-43083
metacyc.compound:CPD-6602
patent:DE859145
patent:KR20130050834
pdb-ccd:CC9
reaxys:2306965
wikipedia.en:Curcumin

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:3962`	curcumin	`antibioticmech:chebi-c5a6336f21`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.