AntibioticMech

diethylstilbestrol

CHEBI:41922 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:26195 CHEBI:26195
• CHEBI:78840 CHEBI:78840

Chemical structure

Computed structure properties

Molecular formula	C18H20O2
Charge	0
Average mass	268.356 Da
Monoisotopic mass	268.14633 Da
Source	ChEBI
InChIKey	RGLYKWWBQGJZGM-ISLYRVAYSA-N

SMILES

CC/C(=C(/CC)c1ccc(O)cc1)c1ccc(O)cc1

InChI

InChI=1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+

Also called

• Distilbene (BRAND_NAME)— chebi
• diethylstilbestrolum (INN)— chebi
• dietilestilbestrol (INN)— chebi
• diéthylstilbestrol (INN)— chebi
• 4,4'-(3E)-hex-3-ene-3,4-diyldiphenol (EXACT_SYNONYM)— chebi
• (E)-3,4-bis(4-hydroxyphenyl)-3-hexene (EXACT_SYNONYM)— chebi
• (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol (EXACT_SYNONYM)— chebi
• 4,4'-dihydroxy-α,β-diethylstilbene (EXACT_SYNONYM)— chebi
• DES (EXACT_SYNONYM)— chebi
• Diethylstilbestrol (EXACT_SYNONYM)— chebi
• trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol (EXACT_SYNONYM)— chebi
• trans-Diethylstilbesterol (EXACT_SYNONYM)— chebi
• trans-Diethylstilbestrol (EXACT_SYNONYM)— chebi
• trans-Diethylstilboesterol (EXACT_SYNONYM)— chebi
• α,α'-diethyl-(E)-4,4'-stilbenediol (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• beilstein:2056095
• cas:56-53-1
• drugbank:DB00255
• drugcentral:875
• foodb.food:FDB007498
• hmdb:HMDB0014400
• kegg.compound:C07620
• kegg.drug:D00577
• pdb-ccd:DES
• wikipedia.en:Diethylstilbestrol

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:41922	diethylstilbestrol	antibioticmech:chebi-a28eb85b0b	2026-08-30

Mechanism summary

Clinical status

APPROVED

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

5. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.