edifenphos

CHEBI:34735 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

An organic thiophosphate that is the O-ethyl-S,S-diphenyl ester of phosphorodithioic acid. Used to control a variety of fungal diseases on rice including blast, ear blight and stem rot. Edifenphos is moderately toxic to mammals and fish but poses more of a risk to aquatic invertebrates. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:37512 CHEBI:37512

Chemical structure

Computed structure properties
Molecular formula	C14H15O2PS2
Charge	0
Average mass	310.38 Da
Monoisotopic mass	310.02511 Da
Source	ChEBI
InChIKey	AWZOLILCOUMRDG-UHFFFAOYSA-N

SMILES

CCOP(=O)(Sc1ccccc1)Sc1ccccc1

InChI

InChI=1S/C14H15O2PS2/c1-2-16-17(15,18-13-9-5-3-6-10-13)19-14-11-7-4-8-12-14/h3-12H,2H2,1H3

Also called

O-ethyl S,S-diphenyl phosphorodithioate (EXACT_SYNONYM)— chebi
BAY 78418 (EXACT_SYNONYM)— chebi
Bayer 78418 (EXACT_SYNONYM)— chebi
EDDP (EXACT_SYNONYM)— chebi
Edifenphos (EXACT_SYNONYM)— chebi
Ediphenophos (EXACT_SYNONYM)— chebi
O-Ethyl-S,S-diphenyl dithiophosphate (EXACT_SYNONYM)— chebi
Phosphorodithioic acid, O-ethyl-S,S-diphenyl ester (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:17109-49-8
hmdb:HMDB0031781
kegg.compound:C14436
pesticides:edifenphos
ppdb:1205
reaxys:1988797

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:86328 CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:34735`	edifenphos	`antibioticmech:chebi-9fa8bd38bb`	2026-08-30

Mechanism summary

Mode of action: CELL_MEMBRANE_SYNTHESIS_INHIBITION host shared target — Assigned from ChEBI role CHEBI:83741 (phospholipid biosynthesis inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.