fenbuconazole

CHEBI:83920 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

Fenbuconazole is a triazole fungicide intended for use as an agricultural and horticultural fungicide spray. It is a systemic protectant and curative which acts by inhibiting sterol biosynthesis in fungi. Fenbuconazole is rapidly absorbed and eliminated, mainly in the faeces through significant biliary excretion; there was no evidence of significant retention in tissues. Fenbuconazole was of low acute toxicity when administered orally (LD50 > 2000 mg/kg bw), dermally (LD50 > 5000 mg/kg bw), or by inhalation (LC50 > 2.1 mg/litre air). It was not irritating to the skin or eyes. — PMID:30870889

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

triazole antifungalARO:3007499

Strictly broader compounds or drug classes this molecule belongs to.

ARO:3007499 ARO:3007499

Chemical structure

Computed structure properties
Molecular formula	C19H17ClN4
Charge	0
Average mass	336.826 Da
Monoisotopic mass	336.11417 Da
Source	ChEBI
InChIKey	RQDJADAKIFFEKQ-UHFFFAOYSA-N

SMILES

N#CC(CCc1ccc(Cl)cc1)(Cn1cncn1)c1ccccc1

InChI

InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009212`	fenbuconazole	`antibioticmech:aro-1755b9e4af`	2026-08-30

Resistance mechanisms

1 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 1

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Colletotrichum truncatum cyp51a with mutations associated with resistance to fenbuconazole	ARO:3009211	not organism-specific	—	ARO:3009211 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009212 (fenbuconazole); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.