fenbuconazole

CHEBI:83920 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

Fenbuconazole is a triazole fungicide intended for use as an agricultural and horticultural fungicide spray. It is a systemic protectant and curative which acts by inhibiting sterol biosynthesis in fungi. Fenbuconazole is rapidly absorbed and eliminated, mainly in the faeces through significant biliary excretion; there was no evidence of significant retention in tissues. Fenbuconazole was of low acute toxicity when administered orally (LD50 > 2000 mg/kg bw), dermally (LD50 > 5000 mg/kg bw), or by inhalation (LC50 > 2.1 mg/litre air). It was not irritating to the skin or eyes. — PMID:30870889

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

triazole antifungalARO:3007499

Strictly broader compounds or drug classes this molecule belongs to.

triazole antifungal ARO:3007499

Chemical structure

Computed structure properties
Molecular formula	C19H17ClN4
Charge	0
Average mass	336.826 Da
Monoisotopic mass	336.11417 Da
Source	ChEBI
InChIKey	RQDJADAKIFFEKQ-UHFFFAOYSA-N

SMILES

N#CC(CCc1ccc(Cl)cc1)(Cn1cncn1)c1ccccc1

InChI

InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009212`	fenbuconazole	`antibioticmech:aro-1755b9e4af`	2026-08-30

Resistance mechanisms

1 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

ANTIBIOTIC_TARGET_ALTERATION 1

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Colletotrichum truncatum cyp51a with mutations associated with resistance to fenbuconazole	ARO:3009211	not organism-specific	—	ARO:3009211 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009212 (fenbuconazole); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (fenbuconazole) · CultureMech · NaturalProductMech · PathwayMech · TraitMech