flutolanil

CHEBI:81792 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of benzamides, obtained by formal condensation of the carboxy group of 2-(trifluoromethyl)benzoic acid with the amino group of 3-(ispropyloxy)aniline. A fungicide used to control a range of pathogens especially Rhizoctonia spp. on rice, turf and other crops. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:22702 CHEBI:22702
CHEBI:35618 CHEBI:35618
CHEBI:83565 CHEBI:83565
CHEBI:87018 CHEBI:87018

Chemical structure

Computed structure properties
Molecular formula	C17H16F3NO2
Charge	0
Average mass	323.314 Da
Monoisotopic mass	323.11331 Da
Source	ChEBI
InChIKey	PTCGDEVVHUXTMP-UHFFFAOYSA-N

SMILES

CC(C)Oc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1

InChI

InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)

Also called

Moncut (BRAND_NAME)— chebi
N-[3-(propan-2-yloxy)phenyl]-2-(trifluoromethyl)benzamide (EXACT_SYNONYM)— chebi
3'-isopropoxy-2-trifloromethylbenzoic acid anilide (EXACT_SYNONYM)— chebi
N-(3-(1-Methylethoxy)phenyl)-2-(trifluoromethyl)benzamide (EXACT_SYNONYM)— chebi
N-(3-isopropoxyphenyl)-2-(trifluoromethyl)benzamide (EXACT_SYNONYM)— chebi
NNF-136 (EXACT_SYNONYM)— chebi
alpha,alpha,alpha-Trifluoro-3'-isopropoxy-o-toluanilide (EXACT_SYNONYM)— chebi
o-trifluoromethyl-m'-isopropoxybenzoic anilide (EXACT_SYNONYM)— chebi
α,α,α-trifluoro-3'-isopropoxy-o-toluanilide (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:66332-96-5
kegg.compound:C18502
metacyc.compound:CPD-15890
pdb-ccd:FTN
pesticides:flutolanil
ppdb:352
reaxys:2163858

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:24127 CHEBI:24127
CHEBI:35718 CHEBI:35718
CHEBI:86328 CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:81792`	flutolanil	`antibioticmech:chebi-96cf27e977`	2026-08-30

Mechanism summary

Mode of action: ENERGY_METABOLISM_INHIBITION host shared target — Assigned from ChEBI role CHEBI:83072 (EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.