AntibioticMech

hamacanthin A

CHEBI:66000 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of pyrazinones that is 5,6-dihydropyrazin-2(1H)-one substituted at positions 3 and 6 by 6-bromo-1H-indol-3-yl groups. It is an antifungal drug isolated from deep water marine sponge Hamacantha sp. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:167376 CHEBI:167376
• CHEBI:24995 CHEBI:24995
• CHEBI:37141 CHEBI:37141
• CHEBI:38958 CHEBI:38958

Chemical structure

Computed structure properties

Molecular formula	C20H14Br2N4O
Charge	0
Average mass	486.167 Da
Monoisotopic mass	483.95344 Da
Source	ChEBI
InChIKey	MYXLDFYXMNSXDR-UHFFFAOYSA-N

SMILES

O=C1NCC(c2cnc3cc(Br)ccc23)N=C1c1cnc2cc(Br)ccc12

InChI

InChI=1S/C20H14Br2N4O/c21-10-1-3-12-14(7-23-16(12)5-10)18-9-25-20(27)19(26-18)15-8-24-17-6-11(22)2-4-13(15)17/h1-8,18,23-24H,9H2,(H,25,27)

Also called

• 3,6-bis(6-bromo-1H-indol-3-yl)-5,6-dihydropyrazin-2(1H)-one (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:160098-92-0

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:66000	hamacanthin A	antibioticmech:chebi-26061d08c1	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.