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iprodione

CHEBI:28909 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Chemical structure

Computed structure properties
Molecular formulaC13H13Cl2N3O3
Charge0
Average mass330.171 Da
Monoisotopic mass329.0334 Da
SourceChEBI
InChIKeyONUFESLQCSAYKA-UHFFFAOYSA-N

SMILES

CC(C)NC(=O)N1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1=O

InChI

InChI=1S/C13H13Cl2N3O3/c1-7(2)16-12(20)17-6-11(19)18(13(17)21)10-4-8(14)3-9(15)5-10/h3-5,7H,6H2,1-2H3,(H,16,20)

Also called

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
SourceNative IDLabelMinted CURIEVersion
CHEBI CHEBI:28909 iprodione antibioticmech:chebi-c230774277 2026-08-30

Resistance mechanisms

15 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

UNKNOWN 15
UNKNOWN
DeterminantARO IDOrganismGene familiesEvidence
Bos1(18.3 (55bp) duplication 835 + 838stop) (amino acid insertion and mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review ren-2016-bt6-4-subject-context: Parent replaced with documented tested descendant; B05.10 identifiers remain reference-only. Association is not causation; source biology retained. EC50 is not MIC. Original source background label: Bt6-4. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain Bt6-4R1
PHIPO:0000389		 —
  • PMID:30686204 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1094/pdis-11-15-1290-re (Identifier-scope review: Tables 2, 3 and 5: publisher-indexed primary text; direct fetch unavailable, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; B05.10 reference taxonomy. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
Bos1(E253D) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review ren-2016-bt3-4-subject-context: Parent replaced with documented tested descendant; B05.10 identifiers remain reference-only. Association is not causation; source biology retained. EC50 is not MIC. Original source background label: Bt3-4. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain Bt3-4R
PHIPO:0000389		 —
  • PMID:30686204 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1094/pdis-11-15-1290-re (Identifier-scope review: Tables 2, 3 and 5: publisher-indexed primary text; direct fetch unavailable, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; B05.10 reference taxonomy. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
Bos1(G415D) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review ren-2016-yc-6-subject-context: Parent replaced with documented tested descendant; B05.10 identifiers remain reference-only. Association is not causation; source biology retained. EC50 is not MIC. Original source background label: Yc-6. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain Yc-6R1
PHIPO:0000389		 —
  • PMID:30686204 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1094/pdis-11-15-1290-re (Identifier-scope review: Tables 2, 3 and 5: publisher-indexed primary text; direct fetch unavailable, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; B05.10 reference taxonomy. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
Bos1(Q846stop) (nonsense mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review ren-2016-nj5-10-subject-context: Parent replaced with documented tested descendant; B05.10 identifiers remain reference-only. Association is not causation; source biology retained. EC50 is not MIC. Original source background label: Nj5-10. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain Nj5-10R
PHIPO:0000389		 —
  • PMID:30686204 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1094/pdis-11-15-1290-re (Identifier-scope review: Tables 2, 3 and 5: publisher-indexed primary text; direct fetch unavailable, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; B05.10 reference taxonomy. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
Hog1::Hyg (disruption) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review mehrabi-2006-parent-reference-context: IPO323 is retained as parent background, not a unique tested derivative. The primary table separates a grouped set of three derivatives from wild-type and ectopic controls. Q1KTF2 and TaxID 336722 identify IPO323 reference context; Mycgr3T76502 is retained as a reference locus, not an experimental allele identifier. The source Not assayed flag remains unchanged and unresolved against the grouped primary comparison. No individual clone, experimental accession, genome or numeric measurement is inferred. Reference-only source identifiers: strain_taxon_id=NCBITaxon:336722; protein_accession=UniProtKB:Q1KTF2.		 — Zymoseptoria tritici NCBITaxon:1047171
strain IPO323 Mycgr3T76502
PHIPO:0000389		 —
  • PMID:17073308 (PHI-base primary-literature antimicrobial interaction PHIG:9481; joined to this record by exact ChEBI identifier.)
  • DOI:10.1094/mpmi-19-1262 (Identifier-scope review: Author-uploaded published paper, web-extracted PDF text: p. 1262 source deposit; p. 1266 Table 2 and footnotes distinguish grouped subjects from controls; p. 1267 identifies IPO323 as parent; direct download HTTP 403, no local PDF or visual page review, UniProtKB release 2026_03: Q1KTF2 entry 108, sequence version 2; source-paper reference and DQ432031 cross-reference; Mycgr3T76502 reference locus; TaxID 336722 under species 1047171. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
Hog1delta (deletion) associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review ma-2024-reference-context: The source label Scl02-05 is retained as background context, not a uniquely resolved tested subject. A7EQI8, A7F519 and TaxID 665079 describe the 1980 / Ss-1 reference strain, not verified Scl02-05 or derivative accessions. Limited primary-supplement identity evidence distinguishes these backgrounds but does not establish a one-to-one source-row/subject crosswalk. Species 5180 is retained. Source alteration, phenotype, assay and mechanism remain unchanged and are not independently validated by this identifier review. Main-text assessment, exact experimental protein and genome identity remain unresolved; no measurement or new allele assignment is inferred. Reference-only source identifiers: strain_taxon_id=NCBITaxon:665079; protein_accession=UniProtKB:A7EQI8.		 — Sclerotinia sclerotiorum NCBITaxon:5180
strain Scl02-05
PHIPO:0000389		 —
  • PMID:38374637 (PHI-base primary-literature antimicrobial interaction PHIG:10483; joined to this record by exact ChEBI identifier.)
  • DOI:10.1021/acs.jafc.3c08093.s001 (Identifier-scope review: Public publisher supplement version 1, PDF p. 5: opening subject-label lines of Figure S4 caption, text-extracted and visually inspected as a crop; distinguishes 1980 UF-70, Scl02-05 and derived subjects; main text and experimental results not fully inspected, UniProtKB release 2026_03: A7EQI8 entry 111 and A7F519 entry 97, sequence versions 1; both unreviewed entries assigned to reference strain ATCC 18683 / 1980 / Ss-1, TaxID 665079, UniProt Taxonomy release 2026_03: 665079 has strain rank under species 5180; metadata retrieved 2026-10-12; no NCBI endpoint request. Reviewed 2026-10-12 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Macroscopic observation (qualitative observation)
Shk1delta (deletion) associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review ma-2024-reference-context: The source label Scl02-05 is retained as background context, not a uniquely resolved tested subject. A7EQI8, A7F519 and TaxID 665079 describe the 1980 / Ss-1 reference strain, not verified Scl02-05 or derivative accessions. Limited primary-supplement identity evidence distinguishes these backgrounds but does not establish a one-to-one source-row/subject crosswalk. Species 5180 is retained. Source alteration, phenotype, assay and mechanism remain unchanged and are not independently validated by this identifier review. Main-text assessment, exact experimental protein and genome identity remain unresolved; no measurement or new allele assignment is inferred. Reference-only source identifiers: strain_taxon_id=NCBITaxon:665079; protein_accession=UniProtKB:A7F519.		 — Sclerotinia sclerotiorum NCBITaxon:5180
strain Scl02-05
PHIPO:0000389		 —
  • PMID:38374637 (PHI-base primary-literature antimicrobial interaction PHIG:7818; joined to this record by exact ChEBI identifier.)
  • DOI:10.1021/acs.jafc.3c08093.s001 (Identifier-scope review: Public publisher supplement version 1, PDF p. 5: opening subject-label lines of Figure S4 caption, text-extracted and visually inspected as a crop; distinguishes 1980 UF-70, Scl02-05 and derived subjects; main text and experimental results not fully inspected, UniProtKB release 2026_03: A7EQI8 entry 111 and A7F519 entry 97, sequence versions 1; both unreviewed entries assigned to reference strain ATCC 18683 / 1980 / Ss-1, TaxID 665079, UniProt Taxonomy release 2026_03: 665079 has strain rank under species 5180; metadata retrieved 2026-10-12; no NCBI endpoint request. Reviewed 2026-10-12 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Macroscopic observation (qualitative observation)
bos1(A493T) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(G278D) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(G415D) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(I365S E529A) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(I365S M427T) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(I365S T581P) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(I365S V239F) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay
bos1(I365S) (amino acid mutation) [Not assayed] associated with resistance to iprodione
This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism. Grounding review fillinger-2012-reference-context: B05.10 is retained as parent background, not a unique tested derivative. UniProtKB:A0A384J5Y1 / BCIN_01g06260 and TaxID 332648 identify B05.10 reference context, not an experimental allele. The original-isolate deposits JX192607-JX192631 are not subject accessions for the later Table 3 comparisons. Preserve source alteration, phenotype and assay flags; EC50 and categorical growth endpoints are not MICs. Exact tested clones, proteins and genomes remain unresolved. Reference-only source identifiers: strain_taxon_id=NCBITaxon:332648; protein_accession=UniProtKB:A0A384J5Y1.		 — Botrytis cinerea NCBITaxon:40559
strain B05.10
PHIPO:0000389		 —
  • PMID:22912706 (PHI-base primary-literature antimicrobial interaction PHIG:4721; joined to this record by exact ChEBI identifier.)
  • DOI:10.1371/journal.pone.0042520 (Identifier-scope review: Results section s3d and Table 3: B05.10-derived subjects distinct from original isolates in Table 1, UniProtKB release 2026_03: A0A384J5Y1 entry 36, sequence version 1; reference strain and one-to-many protein cross-references. Reviewed 2026-10-08 by codex; curation/phibase_grounding_reviews.json SHA-256 1f5d50346b2916fce10969afa8d6409ea836dd15e8cf7fe3cfa3a78d6289b4ed.)
Cell growth assay

Curation history

  1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Seeded from data/raw/ inventories (CHEBI)

  2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  4. RESEEDED_FROM_SOURCES 2026-09-02 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  5. RESEEDED_FROM_SOURCES 2026-09-03 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  6. RESEEDED_FROM_SOURCES 2026-09-03 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  7. RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources

    Re-seeded from updated data/raw/ inventories

  8. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Scoped imported iprodione associations to parent background: reference Bos1 protein and B05.10 TaxID are not tested derivative identities. Original deposits remain separate from later subjects; alterations and phenotypes unchanged.

  9. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed the whole-file PHI-base review checksum after seventeen additional identifier-scope corrections; biological fields, activities and decisions unchanged.

  10. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed the whole-file PHI-base review checksum after one yeast identity-scope correction; biological fields, activities and prior decisions unchanged.

  11. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed the whole-file PHI-base review checksum after twelve reference-scope corrections; biological fields, activities and prior decisions unchanged.

  12. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed the shared PHI-base review checksum after nine identifier-scope corrections; previous decisions, biological fields and activities unchanged.

  13. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed the shared PHI-base review checksum after six identifier-scope corrections; previous decisions, biological fields and activities unchanged.

  14. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Corrected parental labels to primary-table tested-subject labels; moved B05.10 reference identifiers into provenance. Source biological fields and activities unchanged. No exact experimental allele, genome or measurement inferred.

  15. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Darlington subject correction; prior review decisions, biological fields and activities unchanged.

  16. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Nakayama reference-scope review; prior decisions, biological fields and activities unchanged.

  17. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Duan reference-scope review; prior decisions, biological fields and activities unchanged.

  18. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Piotrowska parent-reference review; prior decisions, biological fields and activities unchanged.

  19. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Xu subject and species corrections; prior decisions, biological fields and activities unchanged.

  20. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Shima parent-reference review; prior decisions, biological fields and activities unchanged.

  21. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Scoped IPO323 reference protein and strain TaxID to provenance after primary identity review. Parent label, reference locus, source flags, phenotype and activities preserved; grouped subjects not assigned individual accessions.

  22. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-08 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Huang parent-reference review; prior decisions, biological fields and activities unchanged.

  23. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-09 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the HDF1 subject-reference review; prior decisions, biological fields and activities unchanged.

  24. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-09 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the Fouche parent-cohort review; prior decisions, biological fields and activities unchanged.

  25. REVIEWED_RESISTANCE_REFERENCE_CONTEXT 2026-10-09 · codex · LLM-assisted

    Refreshed shared PHI-base review checksum after the SDH8 reference-alias correction; prior decisions, biological fields and activities unchanged.

  26. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-09 · codex · LLM-assisted

    Refreshed the shared PHI-base review checksum after the Posteraro subject-context review; previous decisions, biological fields and activities unchanged.

  27. REVIEWED_RESISTANCE_REFERENCE_CONTEXT 2026-10-12 · codex · LLM-assisted

    Moved reference protein and strain TaxID into provenance for two PHI-base associations after a limited primary-supplement and UniProt identity review. Retained species and source strain label with unresolved subject context; no allele, phenotype, assay, measurement or mechanism changed. Exact experimental accessions remain unresolved.

  28. REVIEWED_RESISTANCE_SUBJECT_CONTEXT 2026-10-13 · codex · LLM-assisted

    Refreshed the shared PHI-base review checksum after one Neurospora subject-context correction; previous decisions, biological fields and activities unchanged.

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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