itraconazole

CHEBI:6076 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

triazole antifungalARO:3007499

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:23697 CHEBI:23697
CHEBI:35618 CHEBI:35618
CHEBI:35727 CHEBI:35727
CHEBI:39430 CHEBI:39430
CHEBI:46848 CHEBI:46848
CHEBI:59779 CHEBI:59779
CHEBI:87071 CHEBI:87071
CHEBI:87101 CHEBI:87101
ARO:3007499 ARO:3007499

Chemical structure

Computed structure properties
Molecular formula	C35H38Cl2N8O4
Charge	0
Average mass	705.647 Da
Monoisotopic mass	704.23931 Da
Source	ChEBI
InChIKey	VHVPQPYKVGDNFY-ZPGVKDDISA-N

SMILES

CCC(C)n1ncn(-c2ccc(N3CCN(c4ccc(OC[C@H]5CO[C@](Cn6cncn6)(c6ccc(Cl)cc6Cl)O5)cc4)CC3)cc2)c1=O

InChI

InChI=1S/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/m0/s1

Also called

2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one (EXACT_SYNONYM)— chebi
Itraconazole (EXACT_SYNONYM)— chebi
Itrizole (TN) (EXACT_SYNONYM)— chebi
Oriconazole (EXACT_SYNONYM)— chebi
Sporanox (TN) (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

ARO:3007511
cas:84625-61-6
drugbank:DB01167
kegg.drug:D00350
patent:EP6711
patent:US4267179
vsdb:1853
wikipedia.en:Itraconazole
chembl:CHEMBL64391
pubchem.compound:55283

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:35718 CHEBI:35718
CHEBI:86327 CHEBI:86327

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3007511`	itraconazole	`antibioticmech:aro-47bcb54181`	2026-08-30
CHEBI	`CHEBI:6076`	itraconazole	`antibioticmech:chebi-126890f8e2`	2026-08-30

Mechanism summary

Mode of action: ERGOSTEROL_PATHWAY_INHIBITION host shared target — Assigned from ChEBI role CHEBI:75282 (ergosterol biosynthesis inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.
Clinical status: APPROVED

Resistance mechanisms

54 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 24

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Aspergillus awamori Cyp51a with mutations conferring resistance to itraconazole	ARO:3009507	not organism-specific	—	ARO:3009507 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus flavus Cyp51A with mutations conferring resistance to itraconazole	ARO:3009495	not organism-specific	—	ARO:3009495 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus flavus Cyp51c with mutations conferring resistance to itraconazole	ARO:3009282	not organism-specific	—	ARO:3009282 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus fumigatus Hmg1 with mutations conferring resistance to itraconazole	ARO:3009236	not organism-specific	—	ARO:3009236 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus fumigatus Hmg2 with mutations conferring resistance to itraconazole	ARO:3009368	not organism-specific	—	ARO:3009368 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus fumigatus ase1 with mutations conferring resistance to itraconazole	ARO:3009273	not organism-specific	—	ARO:3009273 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus fumigatus cyp51a with mutations conferring resistance to itraconazole	ARO:3009202	not organism-specific	—	ARO:3009202 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus spp. Hmg1 with mutations conferring resistance to triazoles antibiotics	ARO:3007670	not organism-specific	—	ARO:3007670 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus spp. cyp51A with mutations conferring resistance to triazoles antibiotics	ARO:3007565	not organism-specific	—	ARO:3007565 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus terreus cyp51a with mutations conferring resistance to itraconazole	ARO:3009206	not organism-specific	—	ARO:3009206 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus tubingensis Cyp51a with mutations conferring resistance to itraconazole	ARO:3009509	not organism-specific	—	ARO:3009509 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida albicans Cyp51 with mutations conferring resistance to itraconazole	ARO:3009527	not organism-specific	—	ARO:3009527 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida albicans Cyp51a with mutations conferring resistance to itraconazole	ARO:3009505	not organism-specific	—	ARO:3009505 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida albicans Erg11 with mutations conferring resistance to itraconazole	ARO:3009219	not organism-specific	—	ARO:3009219 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida auris ERG11 lanosterol 14-alpha-demethylase with mutations conferring resistance to itraconazole	ARO:3009393	not organism-specific	—	ARO:3009393 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida orthopsilosis ERG11 lanosterol 14-alpha-demethylase with mutations conferring resistance to itraconazole	ARO:3009580	not organism-specific	—	ARO:3009580 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida spp. ERG11 with mutations conferring resistance to azole antibiotics	ARO:3007524	not organism-specific	—	ARO:3007524 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida spp. cyp51A1 with mutations conferring resistance to triazoles and imidazole antibiotics	ARO:3007666	not organism-specific	—	ARO:3007666 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida tropicalis Erg11 lanosterol 14-alpha-demethylase with mutations conferring resistance to itraconazole	ARO:3009583	not organism-specific	—	ARO:3009583 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Colletotrichum truncatum cyp51a with mutations associated with resistance to itraconazole	ARO:3009217	not organism-specific	—	ARO:3009217 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Cryptococcus neoformans Erg11 lanosterol 14-alpha-demethylase with mutations conferring resistance to itraconazole	ARO:3009586	not organism-specific	—	ARO:3009586 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Nakaseomyces glabratus FKS1 beta-1,3-glucan synthase with mutations associated with resistance to itraconazole	ARO:3009614	not organism-specific	—	ARO:3009614 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Nakaseomyces glabratus FKS2 beta-1,3-glucan synthase with mutations associated with resistance to itraconazole	ARO:3009618	not organism-specific	—	ARO:3009618 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Saccharomyces cerevisiae ERG11 lanosterol 14-alpha-demethylase with mutations conferring resistance to itraconazole	ARO:3009589	not organism-specific	—	ARO:3009589 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)

UNKNOWN 21

UNKNOWN
Determinant	ARO ID	Organism	Gene families	Evidence
Aspergillus fumigatus HapE with mutations associated with resistance to itraconazole	ARO:3009294	not organism-specific	—	ARO:3009294 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
CYP51A transformant(CM2627-CYP51Apromoter(2x34bp tandem repeat) and CM2627-CYP51A(L98H)) (transformant) [Overexpression] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CM237 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:17371828 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
Candida albicans TAC1 with mutations conferring resistance to itraconazole	ARO:3009428	not organism-specific	—	ARO:3009428 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
ERG11(Y132F F145L) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Candida albicans `NCBITaxon:5476` strain SC5314 `NCBITaxon:237561` `UniProtKB:P10613` C5_00660C_A-T `PHIPO:0000675`	—	PMID:25385095 (PHI-base primary-literature antimicrobial interaction PHIG:1132; joined to this record by exact ChEBI identifier.) Cell growth assay
ERG3delta (deletion) associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Candida albicans `NCBITaxon:5476` strain SC5314 `NCBITaxon:237561` `UniProtKB:Q59VG6` C1_04770C_A-T `PHIPO:0000675`	—	PMID:28630186 (PHI-base primary-literature antimicrobial interaction PHIG:1133; joined to this record by exact ChEBI identifier.) Cell growth assay
ERG3delta (deletion) associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Candida parapsilosis `NCBITaxon:5480` strain Unknown strain `NCBITaxon:578454` `UniProtKB:G8B7T4` `PHIPO:0000675`	—	PMID:28630186 (PHI-base primary-literature antimicrobial interaction PHIG:8772; joined to this record by exact ChEBI identifier.) Cell growth assay
HapE transformant(Isolate3-HapE(P88L)) (transformant) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain akuBKU80 `NCBITaxon:330879` `UniProtKB:Q4WDM9` `PHIPO:0000675`	—	PMID:23226235 (PHI-base primary-literature antimicrobial interaction PHIG:8691; joined to this record by exact ChEBI identifier.) Cell growth assay
algAdelta (deletion) associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain A1160C `NCBITaxon:451804` `UniProtKB:B0XYD8` `PHIPO:0000675`	—	PMID:27799210 (PHI-base primary-literature antimicrobial interaction PHIG:8688; joined to this record by exact ChEBI identifier.) Cell growth assay
cox10 transformant(W004-cox10(R243Q)) (transformant) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain A1160C `NCBITaxon:451804` `UniProtKB:B0Y628` `PHIPO:0000675`	—	PMID:27799210 (PHI-base primary-literature antimicrobial interaction PHIG:8689; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A transformant(H10-1-50A-cyp51A(N22D)) (transformant) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CEA17 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:15504870 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A transformant(H10-2-50A-cyp51A(M220I)) (transformant) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CEA17 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:15504870 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A transformant(W601-cyp51A(F219L)) (transformant) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain A1160C `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:27799210 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(G54E) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CM237 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:12604551 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(G54E) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain H11-20 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:12709346 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(G54K) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain H11-20 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:12709346 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(G54R) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain ND158 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:12543662 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(G54R) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain H11-20 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:12709346 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(G54W) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain ND158 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:12543662 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(M220K) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CM237 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:15215142 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(M220T) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CM237 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:15215142 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay
cyp51A(M220V) (amino acid mutation) [Not assayed] associated with resistance to itraconazole This is a curated gene-alteration/chemical resistance association, not evidence for a specific biochemical resistance mechanism.	—	Aspergillus fumigatus `NCBITaxon:746128` strain CM237 `NCBITaxon:330879` `UniProtKB:Q4WNT5` Afu4g06890-T `PHIPO:0000675`	—	PMID:15215142 (PHI-base primary-literature antimicrobial interaction PHIG:1837; joined to this record by exact ChEBI identifier.) Cell growth assay

ANTIBIOTIC_EFFLUX 9

ANTIBIOTIC_EFFLUX
Determinant	ARO ID	Organism	Gene families	Evidence
Aspergillus fumigatus MDR3 with mutations conferring resistance to itraconazole	ARO:3009452	not organism-specific	—	ARO:3009452 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Aspergillus fumigatus MDR4 with mutations conferring resistance to itraconazole	ARO:3009453	not organism-specific	—	ARO:3009453 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Candida albicans MDR1 with mutations conferring resistance to itraconazole	ARO:3009448	not organism-specific	—	ARO:3009448 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Cryptococcus neoformans AFR1 with mutations conferring resistance against itraconazole	ARO:3009434	not organism-specific	—	ARO:3009434 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Trychophyton rubrum Mdr2 with mutations associated with resistance to itraconazole	ARO:3009253	not organism-specific	—	ARO:3009253 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Trychophyton rubrum Mdr3 with mutations associated with resistance to itraconazole	ARO:3009255	not organism-specific	—	ARO:3009255 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Trychophyton rubrum Mdr5 with mutations associated with resistance to itraconazole	ARO:3009259	not organism-specific	—	ARO:3009259 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
Trychophyton rubrum Mfs1 with mutations associated with resistance to itraconazole	ARO:3009262	not organism-specific	—	ARO:3009262 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)
fungal MDR	ARO:3009425	not organism-specific	—	ARO:3009425 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3007511 (itraconazole); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-02 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-03 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-03 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.