jervine

CHEBI:6088 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A steroid alkaloid with formula C27H39NO3. It is a natural product isolated from several Veratrum species and exhibits teratogenic activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:26767
Label unavailable CHEBI:33599
Label unavailable CHEBI:35681
Label unavailable CHEBI:50995
Label unavailable CHEBI:51914

Chemical structure

Computed structure properties
Molecular formula	C27H39NO3
Charge	0
Average mass	425.613 Da
Monoisotopic mass	425.29299 Da
Source	ChEBI
InChIKey	CLEXYFLHGFJONT-DNMILWOZSA-N

SMILES

[H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])C(=O)C1=C(C)[C@]3(CC[C@]12[H])O[C@]1([H])C[C@H](C)CN[C@@]1([H])[C@H]3C

InChI

InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1

Also called

(22S,23R)-3β-hydroxy-17β-17,23-epoxyveratraman-11-one (EXACT_SYNONYM)— chebi
(3β,23β)-17,23-epoxy-3-hydroxyveratraman-11-one (EXACT_SYNONYM)— chebi
11-ketocyclopamine (EXACT_SYNONYM)— chebi
3β-hydroxy-17β,23β-epoxyveratraman-11-one (EXACT_SYNONYM)— chebi
jervin (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

wikipedia.en:Jervine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antifungal agent CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:6088`	jervine	`antibioticmech:chebi-916ce2c826`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (jervine) · CultureMech · NaturalProductMech · PathwayMech · TraitMech