kresoxim-methyl

CHEBI:2962 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

strobilurin fungicideARO:3009305

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:25248
Label unavailable CHEBI:35618
Label unavailable CHEBI:36816
Label unavailable CHEBI:86488
strobilurin fungicide ARO:3009305

Chemical structure

Computed structure properties
Molecular formula	C18H19NO4
Charge	0
Average mass	313.353 Da
Monoisotopic mass	313.13141 Da
Source	ChEBI
InChIKey	ZOTBXTZVPHCKPN-HTXNQAPBSA-N

SMILES

CO/N=C(/C(=O)OC)c1ccccc1COc1ccccc1C

InChI

InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+

Also called

methyl (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetate (EXACT_SYNONYM)— chebi
BAS 490 F (EXACT_SYNONYM)— chebi
Methyl (E)-alpha-(methoxyimino)-2-((2-methylphenoxy)methyl)benzeneacetate (EXACT_SYNONYM)— chebi
methyl (E)-methoxyimino[α-(o-tolyloxy)-o-tolyl]acetate (EXACT_SYNONYM)— chebi
methyl (αE)-α-(methoxyimino)-2-[(2-methylphenoxy)methyl]benzeneacetate (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antifungal agent CHEBI:35718
antifungal agrochemical CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009307`	kresoxim-methyl	`antibioticmech:aro-560ad1417d`	2026-08-30
CHEBI	`CHEBI:2962`	kresoxim-methyl	`antibioticmech:chebi-6715ce8bf2`	2026-08-30

Mechanism summary

Mode of action: ENERGY_METABOLISM_INHIBITION host shared target — Assigned from ChEBI role CHEBI:38499 (mitochondrial cytochrome-bc1 complex inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Resistance mechanisms

1 source-backed resistance determinants or associations, with ARO grounding where reported. Grouped by reported mechanism type.

ANTIBIOTIC_TARGET_ALTERATION 1

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Colletotrichum gloeosporioides cytochrome b protein with mutations associated with resistance to kresoxim-methyl	ARO:3009281	not organism-specific	—	ARO:3009281 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009307 (kresoxim-methyl); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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