mepronil

CHEBI:81823 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of benzamides, obtained by formal condensation of the carboxy group of 2-methylbenzoic acid with the amino group of 3-(ispropyloxy)aniline. A fungicide used to control diseases caused by Basidomycetes including Rhizoctonia and Puccinia spp. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:22702 CHEBI:22702
CHEBI:35618 CHEBI:35618
CHEBI:87018 CHEBI:87018

Chemical structure

Computed structure properties
Molecular formula	C17H19NO2
Charge	0
Average mass	269.344 Da
Monoisotopic mass	269.14158 Da
Source	ChEBI
InChIKey	BCTQJXQXJVLSIG-UHFFFAOYSA-N

SMILES

Cc1ccccc1C(=O)Nc1cccc(OC(C)C)c1

InChI

InChI=1S/C17H19NO2/c1-12(2)20-15-9-6-8-14(11-15)18-17(19)16-10-5-4-7-13(16)3/h4-12H,1-3H3,(H,18,19)

Also called

Basitac (BRAND_NAME)— chebi
2-Methyl-3'-isopropoxybenzanilide (EXACT_SYNONYM)— chebi
2-Methyl-N-(3-(1-methylethoxy)phenyl)benzamide (EXACT_SYNONYM)— chebi
2-methyl-N-[3-(propan-2-yloxy)phenyl]benzamide (EXACT_SYNONYM)— chebi
3'-Isopropoxy-2-methylbenzanilide (EXACT_SYNONYM)— chebi
3'-Isopropoxy-o-toluanilide (EXACT_SYNONYM)— chebi
3'-isopropoxy-2-methylbenzoic acid anilide (EXACT_SYNONYM)— chebi
B1-2459 (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:55814-41-0
kegg.compound:C18548
patent:NZ548018
pdb-ccd:MRN
pesticides:mepronil
ppdb:438
reaxys:2381749

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:24127 CHEBI:24127
CHEBI:35718 CHEBI:35718
CHEBI:86328 CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:81823`	mepronil	`antibioticmech:chebi-fc5be72fbe`	2026-08-30

Mechanism summary

Mode of action: ENERGY_METABOLISM_INHIBITION host shared target — Assigned from ChEBI role CHEBI:83072 (EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.