AntibioticMech

N-[5-(1-naphthylmethyl)-1,3-thiazol-2-yl]cyclohexanecarboxamide

CHEBI:76002 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A monocarboxylic acid amide obtained by the formal condensation of cyclohexanecarboxylic acid with the amino group of 5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-amine. It has been shown to exhibit antifungal activity. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:25477 CHEBI:25477
• CHEBI:29347 CHEBI:29347
• CHEBI:38418 CHEBI:38418

Chemical structure

Computed structure properties

Molecular formula	C21H22N2OS
Charge	0
Average mass	350.487 Da
Monoisotopic mass	350.14528 Da
Source	ChEBI
InChIKey	WJAMFZVSJYMDDT-UHFFFAOYSA-N

SMILES

O=C(Nc1ncc(Cc2cccc3ccccc23)s1)C1CCCCC1

InChI

InChI=1S/C21H22N2OS/c24-20(16-8-2-1-3-9-16)23-21-22-14-18(25-21)13-17-11-6-10-15-7-4-5-12-19(15)17/h4-7,10-12,14,16H,1-3,8-9,13H2,(H,22,23,24)

Also called

• N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]cyclohexanecarboxamide (EXACT_SYNONYM)— chebi
• 41F5 (EXACT_SYNONYM)— chebi

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:76002	N-[5-(1-naphthylmethyl)-1,3-thiazol-2-yl]cyclohexanecarboxamide	antibioticmech:chebi-d4f47ddc37	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.