OSU-03012

CHEBI:131196 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of pyrazoles that is N-[4-(pyrazol-1-yl)phenyl]glycinamide in which the pyrazole ring is substituted at positions 3 and 5 by trifluoromethyl and phenanthrene-2-yl groups respectively. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:24373 CHEBI:24373
CHEBI:25961 CHEBI:25961
CHEBI:26410 CHEBI:26410
CHEBI:37143 CHEBI:37143
CHEBI:62733 CHEBI:62733
CHEBI:87113 CHEBI:87113

Chemical structure

Computed structure properties
Molecular formula	C26H19F3N4O
Charge	0
Average mass	460.459 Da
Monoisotopic mass	460.1511 Da
Source	ChEBI
InChIKey	YULUCECVQOCQFQ-UHFFFAOYSA-N

SMILES

NCC(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc3c(ccc4ccccc43)c2)cc1

InChI

InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)

Also called

N-{4-[5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}glycinamide (EXACT_SYNONYM)— chebi
AR 12 (EXACT_SYNONYM)— chebi
AR-12 (EXACT_SYNONYM)— chebi
OSU 03012 (EXACT_SYNONYM)— chebi
PDK1 inhibitor AR-12 (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:742112-33-0
reaxys:11001693
wikipedia.en:OSU-03012

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:35718 CHEBI:35718
CHEBI:86327 CHEBI:86327

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:131196`	OSU-03012	`antibioticmech:chebi-928ce5530f`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.