AntibioticMech

oxiconazole nitrate

CHEBI:7826 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

An organic nitrate salt resulting from the reaction of equimolar amounts of oxiconazole and nitric acid. An antifungal agent, it is used in creams and powders for the topical treatment of fungal skin infections. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:51085 CHEBI:51085
• CHEBI:87069 CHEBI:87069
• CHEBI:87071 CHEBI:87071

Chemical structure

Computed structure properties

Molecular formula	C18H13Cl4N3O.HNO3
Charge	0
Average mass	492.146 Da
Monoisotopic mass	489.97692 Da
Source	ChEBI
InChIKey	WVNOAGNOIPTWPT-NDUABGMUSA-N

SMILES

Clc1ccc(CO/N=C(\Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1.O=[N+]([O-])O

InChI

InChI=1S/C18H13Cl4N3O.HNO3/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22;2-1(3)4/h1-8,11H,9-10H2;(H,2,3,4)/b24-18+;

Also called

• Myfungar (BRAND_NAME)— chebi
• Oceral (BRAND_NAME)— chebi
• Oxistat (BRAND_NAME)— chebi
• Ro 13-8996 (BRAND_NAME)— chebi
• ST 813 (BRAND_NAME)— chebi
• ST-813 (BRAND_NAME)— chebi
• (1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine nitrate (EXACT_SYNONYM)— chebi
• 1-[(2Z)-2-{[(2,4-dichlorobenzyl)oxy]imino}-2-(2,4-dichlorophenyl)ethyl]-1H-imidazol-3-ium nitrate (EXACT_SYNONYM)— chebi
• 2',4'-dichloro-2-imidazol-1-ylacetophenone (Z)-[OO-(2,4-dichlorobenzyl)oxime] mononitrate (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:64211-46-7
• drugbank:DB00239
• hmdb:HMDB0014384
• kegg.compound:C08075
• kegg.drug:D00885
• patent:DE2657578
• patent:US4124767
• reaxys:6042368

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:35718 CHEBI:35718
• CHEBI:86327 CHEBI:86327

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:7826	oxiconazole nitrate	antibioticmech:chebi-dfcd9391e0	2026-08-30

Mechanism summary

Mode of action

ERGOSTEROL_PATHWAY_INHIBITION host shared target — Assigned from ChEBI role CHEBI:75282 (ergosterol biosynthesis inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Clinical status

APPROVED

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

5. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

6. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.