prothioconazole

antibioticmech:aro-a441fc6b50 ·ANTIFUNGAL ·MINTED SEEDED

Prothioconazole is a member of the class of triazoles that is 1,2,4-triazole-3-thione substituted at position 2 by a 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl group. It is a member of monochlorobenzenes, a tertiary alcohol, a member of cyclopropanes and a thiocarbonyl compound. — PMID:23275516

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

triazole antifungalARO:3007499

Strictly broader compounds or drug classes this molecule belongs to.

ARO:3007499 ARO:3007499

Chemical structure

Computed structure properties
Molecular formula	C14H15Cl2N3OS
Charge	0
Average mass	344.3 Da
Monoisotopic mass	343.0312887 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	MNHVNIJQQRJYDH-UHFFFAOYSA-N

SMILES

C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl

InChI

InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009410`	prothioconazole	`antibioticmech:aro-a441fc6b50`	2026-08-30

Resistance mechanisms

2 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 2

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Pyrenopeziza brassicae Cyp51 with mutations conferring resistance to prothioconazole	ARO:3009537	not organism-specific	—	ARO:3009537 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009410 (prothioconazole); database assertion, not a primary citation.)
Zymoseptoria tritici Cyp51 with mutations conferring resistance to prothioconazole	ARO:3009411	not organism-specific	—	ARO:3009411 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009410 (prothioconazole); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.