pyrazophos

CHEBI:81942 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A profungicide (by hydrolysis of the thionophosphate group to afford the corresponding 2-hydroxypyrazolopyrimidine fungicide), it is used to control Erysiphe, Helminthosporium and Rhynchospium in cereals. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:23990 CHEBI:23990
CHEBI:37512 CHEBI:37512
CHEBI:38669 CHEBI:38669

Chemical structure

Computed structure properties
Molecular formula	C14H20N3O5PS
Charge	0
Average mass	373.371 Da
Monoisotopic mass	373.08613 Da
Source	ChEBI
InChIKey	JOOMJVFZQRQWKR-UHFFFAOYSA-N

SMILES

CCOC(=O)c1cn2nc(OP(=S)(OCC)OCC)cc2nc1C

InChI

InChI=1S/C14H20N3O5PS/c1-5-19-14(18)11-9-17-12(15-10(11)4)8-13(16-17)22-23(24,20-6-2)21-7-3/h8-9H,5-7H2,1-4H3

Also called

ethyl 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (EXACT_SYNONYM)— chebi
2-(O,O-Diethylthionophosphoryl)-5-methyl-6-carbethoxy-pyrazolo-(1,5a)pyrimidine (EXACT_SYNONYM)— chebi
Ethyl 2-((diethoxyphosphinothioyl)oxy)-5-methylpyrazolo(1,5-a)pyrimidine-6-carboxylate (EXACT_SYNONYM)— chebi
O,O-Diethyl O-(5-methyl-6-(ethoxycarbonyl)-pyrazolo-(1,5-a)-pyrimid-2-yl)-thionophosphate (EXACT_SYNONYM)— chebi
O-6-ethoxycarbonyl-5-methylpyrazolo[1,5-a]pyrimidin-2-yl O,O-diethyl phosphorothioate (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:13457-18-6
kegg.compound:C18761
patent:EP0111747
pesticides:pyrazophos
ppdb:566
reaxys:577209

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:136645 CHEBI:136645
CHEBI:86328 CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:81942`	pyrazophos	`antibioticmech:chebi-5e64dfc7ae`	2026-08-30

Mechanism summary

Mode of action: CELL_MEMBRANE_SYNTHESIS_INHIBITION host shared target — Assigned from ChEBI role CHEBI:83741 (phospholipid biosynthesis inhibitor). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.