tolclofos-methyl

CHEBI:81731 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

An organic thiophosphate that is 2,6-dichloro-4-methylphenol in which the hydrogen of the hydroxy group group has been replaced by a dimethoxyphosphorothioyl group. Tolclofos-methyl is a phospholipid biosynthesis inhibitor and fungicide that is used for controlling soil-borne diseases caused by Typhula incarnata, Corticium rolfsii, Typhula ishikariensis, and Rhizoctonia solani. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:23697
Label unavailable CHEBI:37512

Chemical structure

Computed structure properties
Molecular formula	C9H11Cl2O3PS
Charge	0
Average mass	301.131 Da
Monoisotopic mass	299.95436 Da
Source	ChEBI
InChIKey	OBZIQQJJIKNWNO-UHFFFAOYSA-N

SMILES

COP(=S)(OC)Oc1c(Cl)cc(C)cc1Cl

InChI

InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3

Also called

Basilex (BRAND_NAME)— chebi
Grancer (BRAND_NAME)— chebi
Risolex (BRAND_NAME)— chebi
Rizolex (BRAND_NAME)— chebi
O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl phosphorothioate (EXACT_SYNONYM)— chebi
O-(2,6-dichloro-4-methylphenyl)phosphorothioic acid O,O-dimethyl ester (EXACT_SYNONYM)— chebi
O-2,6-dichloro-p-tolyl O,O-dimethyl phosphorothioate (EXACT_SYNONYM)— chebi
S-3349 (EXACT_SYNONYM)— chebi
tolclofos-Me (EXACT_SYNONYM)— chebi
tolclofos-méthyl (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antifungal agrochemical CHEBI:86328

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:81731`	tolclofos-methyl	`antibioticmech:chebi-7fc74626e3`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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