trichostatin A

CHEBI:46024 ·resolve ·ANTIFUNGAL ·EXACT SEEDED

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:24650 CHEBI:24650
CHEBI:39146 CHEBI:39146
CHEBI:86478 CHEBI:86478

Chemical structure

Computed structure properties
Molecular formula	C17H22N2O3
Charge	0
Average mass	302.374 Da
Monoisotopic mass	302.16304 Da
Source	ChEBI
InChIKey	RTKIYFITIVXBLE-QEQCGCAPSA-N

SMILES

CC(/C=C/C(=O)NO)=C\[C@@H](C)C(=O)c1ccc(N(C)C)cc1

InChI

InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1

Also called

(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide (EXACT_SYNONYM)— chebi
(2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide (EXACT_SYNONYM)— chebi
TRICHOSTATIN A (EXACT_SYNONYM)— chebi
TSA (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

beilstein:5291761
cas:58880-19-6
drugbank:DB04297
hmdb:HMDB0259177
knapsack:C00016002
pdb-ccd:TSN
wikipedia.en:Trichostatin_A

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281
CHEBI:35718 CHEBI:35718

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:46024`	trichostatin A	`antibioticmech:chebi-16b9bef7af`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.