triflumizole

antibioticmech:aro-d53850fc72 ·ANTIFUNGAL ·MINTED SEEDED

This compound inhibits sterol 14alpha-demethylase and is used as a fungicide for the control of powdery mildew, scab and other diseases on a variety of crops. It is a member of the following groups: monochlorobenzenes, imidazoles, (trifluoromethyl)benzenes, carboxamidine, ether and conazoles. — PMID:10919801

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

imidazole antibioticARO:3007500

Strictly broader compounds or drug classes this molecule belongs to.

ARO:3007500 ARO:3007500

Chemical structure

Computed structure properties
Molecular formula	C15H15ClF3N3O
Charge	0
Average mass	345.75 Da
Monoisotopic mass	345.0855743 Da
Source	PubChem · retrieved 2026-08-29
InChIKey	HSMVPDGQOIQYSR-UHFFFAOYSA-N

SMILES

CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2

InChI

InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3

Cross-references

Equivalent identifiers for this same structure in other resources.

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3009169`	triflumizole	`antibioticmech:aro-d53850fc72`	2026-08-30

Resistance mechanisms

1 known routes by which microbes resist this compound, grounded in ARO where CARD models them. Grouped by mechanism type — expand a group to see its determinants.

ANTIBIOTIC_TARGET_ALTERATION 1

ANTIBIOTIC_TARGET_ALTERATION
Determinant	ARO ID	Organism	Gene families	Evidence
Zymoseptoria tritici Cyp51 with mutations conferring resistance to triflumazole	ARO:3009404	not organism-specific	—	ARO:3009404 (CARD/ARO asserts confers_resistance_to_antibiotic ARO:3009169 (triflumizole); database assertion, not a primary citation.)

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.