ethambutol dihydrochloride
CHEBI:4878
·resolve ·ANTIMYCOBACTERIAL
·EXACT
SEEDED
The dihydrchloride salt of ethambutol. A bacteriostatic antimycobacterial drug, it is effective against Mycobacterium tuberculosis and some other mycobacteria. It is used in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol dihydrochloride is used alone. — ChEBI
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C10H26N2O2.2Cl |
|---|
| Charge | 0 |
|---|
| Average mass | 277.236 Da |
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| Monoisotopic mass | 276.13713 Da |
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| Source | ChEBI |
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| InChIKey | AUAHHJJRFHRVPV-BZDVOYDHSA-N |
|---|
SMILES
CC[C@@H](CO)[NH2+]CC[NH2+][C@@H](CC)CO.[Cl-].[Cl-]
InChI
InChI=1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1
Also called
- N,N'-bis[(2S)-1-hydroxybutan-2-yl]ethane-1,2-diaminium dichloride (EXACT_SYNONYM)— chebi
- (+)-(S,S)-ethambutol dihydrochloride (EXACT_SYNONYM)— chebi
- (+)-2,2'-(ethylenediimino)-di-1-butanol dihydrochloride (EXACT_SYNONYM)— chebi
- (+)-2,2'-(ethylenediimino)di-1-butanol dihydrochloride (EXACT_SYNONYM)— chebi
- (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine dihydrochloride (EXACT_SYNONYM)— chebi
- (+)-ethambutol dihydrochloride (EXACT_SYNONYM)— chebi
- (2S,2'E)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride (EXACT_SYNONYM)— chebi
- ethambutol HCl (EXACT_SYNONYM)— chebi
- ethambutol hydrochloride (EXACT_SYNONYM)— chebi
Cross-references
Equivalent identifiers for this same structure in other resources.
Activity roles
Every antimicrobial role a source asserts for this compound — the
unreduced evidence behind its antimicrobial_class.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| CHEBI |
CHEBI:4878 |
ethambutol dihydrochloride |
antibioticmech:chebi-2633a6d79a |
2026-08-30 |
Mechanism summary
- Clinical status
- APPROVED
Curation history
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SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
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RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
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RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.