ethambutol dihydrochloride

CHEBI:4878 ·resolve ·ANTIMYCOBACTERIAL ·EXACT SEEDED

The dihydrchloride salt of ethambutol. A bacteriostatic antimycobacterial drug, it is effective against Mycobacterium tuberculosis and some other mycobacteria. It is used in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol dihydrochloride is used alone. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:36807

Chemical structure

Computed structure properties
Molecular formula	C10H26N2O2.2Cl
Charge	0
Average mass	277.236 Da
Monoisotopic mass	276.13713 Da
Source	ChEBI
InChIKey	AUAHHJJRFHRVPV-BZDVOYDHSA-N

SMILES

CC[C@@H](CO)[NH2+]CC[NH2+][C@@H](CC)CO.[Cl-].[Cl-]

InChI

InChI=1S/C10H24N2O2.2ClH/c1-3-9(7-13)11-5-6-12-10(4-2)8-14;;/h9-14H,3-8H2,1-2H3;2*1H/t9-,10-;;/m0../s1

Also called

N,N'-bis[(2S)-1-hydroxybutan-2-yl]ethane-1,2-diaminium dichloride (EXACT_SYNONYM)— chebi
(+)-(S,S)-ethambutol dihydrochloride (EXACT_SYNONYM)— chebi
(+)-2,2'-(ethylenediimino)-di-1-butanol dihydrochloride (EXACT_SYNONYM)— chebi
(+)-2,2'-(ethylenediimino)di-1-butanol dihydrochloride (EXACT_SYNONYM)— chebi
(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine dihydrochloride (EXACT_SYNONYM)— chebi
(+)-ethambutol dihydrochloride (EXACT_SYNONYM)— chebi
(2S,2'E)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride (EXACT_SYNONYM)— chebi
ethambutol HCl (EXACT_SYNONYM)— chebi
ethambutol hydrochloride (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

beilstein:6317056
cas:1070-11-7

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antitubercular agent CHEBI:33231

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:4878`	ethambutol dihydrochloride	`antibioticmech:chebi-2633a6d79a`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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