nothramicin

CHEBI:66638 ·resolve ·ANTIMYCOBACTERIAL ·EXACT SEEDED

An anthracycline antibiotic isolated from the culture broth of Nocardia sp. MJ896-43F17. It exhibits significant antimycobacterial activity against several drug-resistant Mycobacterium smegmatis strains. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:35315 CHEBI:35315
CHEBI:35618 CHEBI:35618
CHEBI:47779 CHEBI:47779
CHEBI:49322 CHEBI:49322
CHEBI:50996 CHEBI:50996

Chemical structure

Computed structure properties
Molecular formula	C30H37NO11
Charge	0
Average mass	587.622 Da
Monoisotopic mass	587.23666 Da
Source	ChEBI
InChIKey	XXHMZNPASHQZPM-UHFFFAOYSA-N

SMILES

COc1ccc(O)c2c1C(=O)c1cc3c(c(O)c1C2=O)C(OC1CC(C)(N(C)C)C(O)C(C)O1)C(OC)C(C)(O)C3O

InChI

InChI=1S/C30H37NO11/c1-12-26(36)29(2,31(4)5)11-17(41-12)42-25-19-14(27(37)30(3,38)28(25)40-7)10-13-18(23(19)34)24(35)20-15(32)8-9-16(39-6)21(20)22(13)33/h8-10,12,17,25-28,32,34,36-38H,11H2,1-7H3

Also called

3,4,10,12-tetrahydroxy-2,7-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)-3-methylhexopyranoside (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:205752-47-2

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281
CHEBI:64912 CHEBI:64912

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:66638`	nothramicin	`antibioticmech:chebi-bde605eb6b`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.