pyrazine-2-carboxylic acid

CHEBI:71311 ·resolve ·ANTIMYCOBACTERIAL ·EXACT SEEDED

The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:48345

Chemical structure

Computed structure properties
Molecular formula	C5H4N2O2
Charge	0
Average mass	124.099 Da
Monoisotopic mass	124.02728 Da
Source	ChEBI
InChIKey	NIPZZXUFJPQHNH-UHFFFAOYSA-N

SMILES

O=C(O)c1cnccn1

InChI

InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9)

Also called

2-Carboxypyrazine (EXACT_SYNONYM)— chebi
2-Pyrazinecarboxylic acid (EXACT_SYNONYM)— chebi
Paradiazinecarboxylic acid (EXACT_SYNONYM)— chebi
Pyrazinemonocarboxylic acid (EXACT_SYNONYM)— chebi
Pyrazinic acid (EXACT_SYNONYM)— chebi
Pyrazinoic acid (EXACT_SYNONYM)— chebi
pyrazinecarboxylic acid (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

wikipedia.en:Pyrazinoic_acid

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antitubercular agent CHEBI:33231

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:71311`	pyrazine-2-carboxylic acid	`antibioticmech:chebi-92a8f07dd3`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (pyrazine-2-carboxylic acid) · CultureMech · NaturalProductMech · PathwayMech · TraitMech