pyrazine-2-carboxylic acid
CHEBI:71311
·resolve ·ANTIMYCOBACTERIAL
·EXACT
SEEDED
The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide. — ChEBI
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C5H4N2O2 |
|---|
| Charge | 0 |
|---|
| Average mass | 124.099 Da |
|---|
| Monoisotopic mass | 124.02728 Da |
|---|
| Source | ChEBI |
|---|
| InChIKey | NIPZZXUFJPQHNH-UHFFFAOYSA-N |
|---|
SMILES
O=C(O)c1cnccn1
InChI
InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9)
Also called
- 2-Carboxypyrazine (EXACT_SYNONYM)— chebi
- 2-Pyrazinecarboxylic acid (EXACT_SYNONYM)— chebi
- Paradiazinecarboxylic acid (EXACT_SYNONYM)— chebi
- Pyrazinemonocarboxylic acid (EXACT_SYNONYM)— chebi
- Pyrazinic acid (EXACT_SYNONYM)— chebi
- Pyrazinoic acid (EXACT_SYNONYM)— chebi
- pyrazinecarboxylic acid (EXACT_SYNONYM)— chebi
Cross-references
Equivalent identifiers for this same structure in other resources.
Activity roles
Every antimicrobial role a source asserts for this compound — the
unreduced evidence behind its antimicrobial_class.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| CHEBI |
CHEBI:71311 |
pyrazine-2-carboxylic acid |
antibioticmech:chebi-92a8f07dd3 |
2026-08-30 |
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.