(R)-N-trans-feruloyloctopamine

CHEBI:67373 ·resolve ·ANTIMYCOBACTERIAL ·EXACT SEEDED

A member of the class of cinnamamides that is an enamide obtained by the formal condensation of the amino group of (R)-octopamine with the carboxy group of ferulic acid. Isolated from Pisonia aculeata, it exhibits antitubercular activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:140325
Label unavailable CHEBI:23247
Label unavailable CHEBI:25235
Label unavailable CHEBI:33853

Chemical structure

Computed structure properties
Molecular formula	C18H19NO5
Charge	0
Average mass	329.352 Da
Monoisotopic mass	329.12632 Da
Source	ChEBI
InChIKey	VJSCHQMOTSXAKB-CFZDNBDDSA-N

SMILES

COc1cc(/C=C/C(=O)NC[C@H](O)c2ccc(O)cc2)ccc1O

InChI

InChI=1S/C18H19NO5/c1-24-17-10-12(2-8-15(17)21)3-9-18(23)19-11-16(22)13-4-6-14(20)7-5-13/h2-10,16,20-22H,11H2,1H3,(H,19,23)/b9-3+/t16-/m0/s1

Also called

(2E)-N-[(2R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide (EXACT_SYNONYM)— chebi
(2S,E)-N-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]ferulamide (EXACT_SYNONYM)— chebi
N-[2-(R)-hydroxy-2-(4-hydroxy-phenyl)ethyl]-3-(4-hydroxy-3-methoxy-phenyl)acrylamide (EXACT_SYNONYM)— chebi
(R)-N-[(E)-feruloyl]octopamine (RELATED_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

reaxys:9579371

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antitubercular agent CHEBI:33231

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:67373`	(R)-N-trans-feruloyloctopamine	`antibioticmech:chebi-323b67c54c`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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