9-methoxycanthin-6-one

CHEBI:66699 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

An indole alkaloid that is the 9-methoxy derivative of canthin-6-one. Isolated from Eurycoma longifolia and Simaba multiflora, it exhibits cytotoxic activity towards human cancer cell lines. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:35618
Label unavailable CHEBI:38163
Label unavailable CHEBI:38958

Chemical structure

Computed structure properties
Molecular formula	C15H10N2O2
Charge	0
Average mass	250.257 Da
Monoisotopic mass	250.07423 Da
Source	ChEBI
InChIKey	OWCRARVHWCCRAG-UHFFFAOYSA-N

SMILES

COc1ccc2c3ccnc4ccc(=O)n(c2c1)c43

InChI

InChI=1S/C15H10N2O2/c1-19-9-2-3-10-11-6-7-16-12-4-5-14(18)17(15(11)12)13(10)8-9/h2-8H,1H3

Also called

9-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one (EXACT_SYNONYM)— chebi
13-methoxy-1,6-diazatetracyclo[7.6.1.0(5,16).0(10,15)]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one (EXACT_SYNONYM)— chebi
8-methoxycanthin-6-one (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

reaxys:4470310

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antiplasmodial drug CHEBI:64915

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:66699`	9-methoxycanthin-6-one	`antibioticmech:chebi-4b5f7d2099`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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