9-methoxycanthin-6-one

CHEBI:66699 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

An indole alkaloid that is the 9-methoxy derivative of canthin-6-one. Isolated from Eurycoma longifolia and Simaba multiflora, it exhibits cytotoxic activity towards human cancer cell lines. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:35618 CHEBI:35618
CHEBI:38163 CHEBI:38163
CHEBI:38958 CHEBI:38958

Chemical structure

Computed structure properties
Molecular formula	C15H10N2O2
Charge	0
Average mass	250.257 Da
Monoisotopic mass	250.07423 Da
Source	ChEBI
InChIKey	OWCRARVHWCCRAG-UHFFFAOYSA-N

SMILES

COc1ccc2c3ccnc4ccc(=O)n(c2c1)c43

InChI

InChI=1S/C15H10N2O2/c1-19-9-2-3-10-11-6-7-16-12-4-5-14(18)17(15(11)12)13(10)8-9/h2-8H,1H3

Also called

9-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one (EXACT_SYNONYM)— chebi
13-methoxy-1,6-diazatetracyclo[7.6.1.0(5,16).0(10,15)]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one (EXACT_SYNONYM)— chebi
8-methoxycanthin-6-one (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

reaxys:4470310

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:64915 CHEBI:64915

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:66699`	9-methoxycanthin-6-one	`antibioticmech:chebi-4b5f7d2099`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.