acedapsone

CHEBI:139474 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

A sulfone that is dapsone in which both of the amino groups been acetylation. An antimicrobial drug, it also has antimalarial activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:13248
Label unavailable CHEBI:140325
Label unavailable CHEBI:22160
Label unavailable CHEBI:35850

Chemical structure

Computed structure properties
Molecular formula	C16H16N2O4S
Charge	0
Average mass	332.381 Da
Monoisotopic mass	332.08308 Da
Source	ChEBI
InChIKey	AMTPYFGPPVFBBI-UHFFFAOYSA-N

SMILES

CC(=O)Nc1ccc(S(=O)(=O)c2ccc(NC(C)=O)cc2)cc1

InChI

InChI=1S/C16H16N2O4S/c1-11(19)17-13-3-7-15(8-4-13)23(21,22)16-9-5-14(6-10-16)18-12(2)20/h3-10H,1-2H3,(H,17,19)(H,18,20)

Also called

acedapsona (INN)— chebi
acedapsonum (INN)— chebi
N,N'-[sulfonyldi(4,1-phenylene)]diacetamide (EXACT_SYNONYM)— chebi
4',4'''-sulfonylbis(acetanilide) (EXACT_SYNONYM)— chebi
N,N'-(sulfonyldi-4,1-phenylene)bisacetamide (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

cas:77-46-3
reaxys:2164071

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

wikipedia.en:Acedapsone

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

antimicrobial drug CHEBI:36043
antimalarial CHEBI:38068

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:139474`	acedapsone	`antibioticmech:chebi-67b5832aab`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

Explore across X-Mech: MediaIngredientMech (acedapsone) · CultureMech · NaturalProductMech · PathwayMech · TraitMech