acedapsone

CHEBI:139474 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

A sulfone that is dapsone in which both of the amino groups been acetylation. An antimicrobial drug, it also has antimalarial activity. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:13248 CHEBI:13248
CHEBI:140325 CHEBI:140325
CHEBI:22160 CHEBI:22160
CHEBI:35850 CHEBI:35850

Chemical structure

Computed structure properties
Molecular formula	C16H16N2O4S
Charge	0
Average mass	332.381 Da
Monoisotopic mass	332.08308 Da
Source	ChEBI
InChIKey	AMTPYFGPPVFBBI-UHFFFAOYSA-N

SMILES

CC(=O)Nc1ccc(S(=O)(=O)c2ccc(NC(C)=O)cc2)cc1

InChI

InChI=1S/C16H16N2O4S/c1-11(19)17-13-3-7-15(8-4-13)23(21,22)16-9-5-14(6-10-16)18-12(2)20/h3-10H,1-2H3,(H,17,19)(H,18,20)

Also called

acedapsona (INN)— chebi
acedapsonum (INN)— chebi
N,N'-[sulfonyldi(4,1-phenylene)]diacetamide (EXACT_SYNONYM)— chebi
4',4'''-sulfonylbis(acetanilide) (EXACT_SYNONYM)— chebi
N,N'-(sulfonyldi-4,1-phenylene)bisacetamide (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:77-46-3
reaxys:2164071
wikipedia.en:Acedapsone

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:36043 CHEBI:36043
CHEBI:38068 CHEBI:38068

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:139474`	acedapsone	`antibioticmech:chebi-67b5832aab`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.