Eunicea sesquiterpenoid 2

CHEBI:65873 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

A eudesmane sesquiterpenoid in which the eudesmane skeleton is substituted with an α-hydroxy group at C-1 (eudesmane numbering) and a methylidene group at C-4, and includes a lactone ring formed between C-12 and a β-hydroxy group at C-6. It is isolated from Eunicea sp. and exhibits significant inhibitory effect upon the growth of the malarial parasite Plasmodium falciparum — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26979 CHEBI:26979
CHEBI:35681 CHEBI:35681
CHEBI:37581 CHEBI:37581
CHEBI:62508 CHEBI:62508

Chemical structure

Computed structure properties
Molecular formula	C15H22O3
Charge	0
Average mass	250.338 Da
Monoisotopic mass	250.15689 Da
Source	ChEBI
InChIKey	JWBPWNWPEVPCMJ-JVFXBBKESA-N

SMILES

[H][C@@]12OC(=O)[C@@H](C)[C@]1([H])CC[C@]1(C)[C@@H](O)CCC(=C)[C@@]21[H]

InChI

InChI=1S/C15H22O3/c1-8-4-5-11(16)15(3)7-6-10-9(2)14(17)18-13(10)12(8)15/h9-13,16H,1,4-7H2,2-3H3/t9-,10-,11-,12-,13+,15+/m0/s1

Also called

(3S,3aS,5aS,6S,9aR,9bR)-6-hydroxy-3,5a-dimethyl-9-methylidenedecahydronaphtho[1,2-b]furan-2(3H)-one (EXACT_SYNONYM)— chebi

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:38068 CHEBI:38068

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:65873`	Eunicea sesquiterpenoid 2	`antibioticmech:chebi-45f546652d`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.