lasalocid

CHEBI:92181 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

A polyether antibiotic used for prevention and treatment of coccidiosis in poultry. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

polyketide with antibiotic activityARO:3005171

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:25384 CHEBI:25384
CHEBI:25389 CHEBI:25389
CHEBI:26179 CHEBI:26179
CHEBI:26878 CHEBI:26878
CHEBI:26912 CHEBI:26912
CHEBI:35681 CHEBI:35681
CHEBI:46942 CHEBI:46942
CHEBI:55380 CHEBI:55380
ARO:3005171 ARO:3005171

Chemical structure

Computed structure properties
Molecular formula	C34H54O8
Charge	0
Average mass	590.798 Da
Monoisotopic mass	590.38187 Da
Source	ChEBI
InChIKey	BBMULGJBVDDDNI-OWKLGTHSSA-N

SMILES

[H][C@]1([C@@H](CC)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc2ccc(C)c(O)c2C(=O)O)O[C@](CC)([C@@]2([H])CC[C@](O)(CC)[C@H](C)O2)C[C@@H]1C

InChI

InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1

Also called

lasalocide (INN)— chebi
lasalocidum (INN)— chebi
lasalócido (INN)— chebi
(1S,9S)-1,5:6,9-dianhydro-9-[(3R,5S,6S,7R)-9-(2-carboxy-3-hydroxy-4-methylphenyl)-6-hydroxy-5,7-dimethyl-4-oxononan-3-yl]-3,4,7,8-tetradeoxy-6-ethyl-2-C-ethyl-1,8-dimethyl-D-galacto-nonitol (EXACT_SYNONYM)— chebi
6-[(3R,4S,5S,7R)-7-{(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-3-methyltetrahydrofuran-2-yl}-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid (EXACT_SYNONYM)— chebi
Ro 2-2985 (EXACT_SYNONYM)— chebi
X 537A (EXACT_SYNONYM)— chebi
X-537A (EXACT_SYNONYM)— chebi
antibiotic X 537A (EXACT_SYNONYM)— chebi
ionophore X 537A (EXACT_SYNONYM)— chebi
lasalocid A (EXACT_SYNONYM)— chebi
Lasalocid (EXACT_SYNONYM)— aro
Lasalocide (EXACT_SYNONYM)— aro

Cross-references

Equivalent identifiers for this same structure in other resources.

ARO:3007754
cas:25999-31-9
drugbank:DB11423
kegg.drug:D04671
lincs.smallmolecule:LSM-2214
lipidmaps:LMPK09000002
pdb-ccd:LSD
wikipedia.en:Lasalocid
chembl:CHEMBL145347
pubchem.compound:5360807

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:33281 CHEBI:33281
CHEBI:35818 CHEBI:35818

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
ARO	`ARO:3007754`	lasalocid A	`antibioticmech:aro-466b335c0d`	2026-08-30
CHEBI	`CHEBI:92181`	lasalocid	`antibioticmech:chebi-6226860c32`	2026-08-30

Mechanism summary

Mode of action: MEMBRANE_DISRUPTION host shared target — Assigned from ChEBI role CHEBI:24869 (ionophore). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (ARO, CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.