lasalocid

CHEBI:92181 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

A polyether antibiotic used for prevention and treatment of coccidiosis in poultry. — ChEBI

Classification

polyketide with antibiotic activityARO:3005171

Strictly broader compounds or drug classes this molecule belongs to.

• Label unavailable CHEBI:25384
• Label unavailable CHEBI:25389
• Label unavailable CHEBI:26179
• Label unavailable CHEBI:26878
• Label unavailable CHEBI:26912
• Label unavailable CHEBI:35681
• Label unavailable CHEBI:46942
• Label unavailable CHEBI:55380
• polyketide with antibiotic activity ARO:3005171

Chemical structure

SMILES

[H][C@]1([C@@H](CC)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc2ccc(C)c(O)c2C(=O)O)O[C@](CC)([C@@]2([H])CC[C@](O)(CC)[C@H](C)O2)C[C@@H]1C

InChI

InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1

Also called

• lasalocide (INN)— chebi
• lasalocidum (INN)— chebi
• lasalócido (INN)— chebi
• (1S,9S)-1,5:6,9-dianhydro-9-[(3R,5S,6S,7R)-9-(2-carboxy-3-hydroxy-4-methylphenyl)-6-hydroxy-5,7-dimethyl-4-oxononan-3-yl]-3,4,7,8-tetradeoxy-6-ethyl-2-C-ethyl-1,8-dimethyl-D-galacto-nonitol (EXACT_SYNONYM)— chebi
• 6-[(3R,4S,5S,7R)-7-{(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-3-methyltetrahydrofuran-2-yl}-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid (EXACT_SYNONYM)— chebi
• Ro 2-2985 (EXACT_SYNONYM)— chebi
• X 537A (EXACT_SYNONYM)— chebi
• X-537A (EXACT_SYNONYM)— chebi
• antibiotic X 537A (EXACT_SYNONYM)— chebi
• ionophore X 537A (EXACT_SYNONYM)— chebi
• lasalocid A (EXACT_SYNONYM)— chebi
• Lasalocid (EXACT_SYNONYM)— aro
• Lasalocide (EXACT_SYNONYM)— aro

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

• lasalocid AARO:3007754
• cas:25999-31-9
• lincs.smallmolecule:LSM-2214
• lipidmaps:LMPK09000002
• pdb-ccd:LSD
• chembl:CHEMBL145347
• pubchem.compound:5360807

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

• drugbank:DB11423
• kegg.drug:D04671

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

• wikipedia.en:Lasalocid

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• antimicrobial agent CHEBI:33281
• coccidiostat CHEBI:35818

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Mechanism summary

Mode of action

MEMBRANE_DISRUPTION host shared target — Assigned from ChEBI role CHEBI:24869 (ionophore). ChEBI asserts the role on the compound. The target it names is one the host has too, so the mechanism is true but is not evidence of selectivity — see mode_of_action_target_scope. Not a curator's mechanistic review.

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (ARO, CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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