suramin sodium

CHEBI:9364 ·resolve ·ANTIPROTOZOAL ·EXACT SEEDED

An organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:38700 CHEBI:38700

Chemical structure

Computed structure properties
Molecular formula	C51H34N6O23S6.6Na
Charge	0
Average mass	1429.194 Da
Monoisotopic mass	1427.93857 Da
Source	ChEBI
InChIKey	VAPNKLKDKUDFHK-UHFFFAOYSA-H

SMILES

Cc1ccc(C(=O)Nc2ccc(S(=O)(=O)[O-])c3cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c23)cc1NC(=O)c1cccc(NC(=O)Nc2cccc(C(=O)Nc3cc(C(=O)Nc4ccc(S(=O)(=O)[O-])c5cc(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c45)ccc3C)c2)c1.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6

Also called

Antrypol (BRAND_NAME)— chebi
Bayer 205 (BRAND_NAME)— chebi
Fourneau 309 (BRAND_NAME)— chebi
Germanin (BRAND_NAME)— chebi
Moranyl (BRAND_NAME)— chebi
Naganin (BRAND_NAME)— chebi
Naganine (BRAND_NAME)— chebi
Naganinum (BRAND_NAME)— chebi
Naganol (BRAND_NAME)— chebi
Naphuride sodium (BRAND_NAME)— chebi
suramina de sodio (INN)— chebi
suramine sodique (INN)— chebi
suraminum natricum (INN)— chebi
hexasodium 8,8'-{carbonylbis[iminobenzene-3,1-diylcarbonylimino(4-methylbenzene-3,1-diyl)carbonylimino]}dinaphthalene-1,3,5-trisulfonate (EXACT_SYNONYM)— chebi
8,8'-[ureylenebis[m-phenylene carbonylimino(4-methyl-m-phenylene)carbonylimino]]di(1,3,5-naphthalenetrisulfonic acid) hexasodium salt (EXACT_SYNONYM)— chebi
BAY 205 (EXACT_SYNONYM)— chebi
CI 1003 (EXACT_SYNONYM)— chebi
CI-1003 (EXACT_SYNONYM)— chebi
NF 060 (EXACT_SYNONYM)— chebi
SK 24728 (EXACT_SYNONYM)— chebi
suramin hexasodium (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:129-46-4
chemspider:5167
drugbank:DBSALT000540
kegg.drug:D00808
patent:US4737521

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:36335 CHEBI:36335

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:9364`	suramin sodium	`antibioticmech:chebi-02683dd918`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.