AntibioticMech

6-bromoharmine

CHEBI:72481 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A member of the class of β-carbolines that is 9H-β-carboline substituted by a bromo group at position 6, a methoxy group at position 7 and a methyl group at position 1. It is semisynthetic derivative of harmine and has been shown to exhibit significant anti-HIV activity. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:35618 CHEBI:35618
• CHEBI:37141 CHEBI:37141
• CHEBI:72588 CHEBI:72588

Chemical structure

Computed structure properties

Molecular formula	C13H11BrN2O
Charge	0
Average mass	291.148 Da
Monoisotopic mass	290.00548 Da
Source	ChEBI
InChIKey	YRYJSDPQWKIQRL-UHFFFAOYSA-N

SMILES

COc1cc2nc3c(C)nccc3c2cc1Br

InChI

InChI=1S/C13H11BrN2O/c1-7-13-8(3-4-15-7)9-5-10(14)12(17-2)6-11(9)16-13/h3-6,16H,1-2H3

Also called

• 6-bromo-7-methoxy-1-methyl-9H-β-carboline (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• reaxys:8490488

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:64946 CHEBI:64946

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:72481	6-bromoharmine	antibioticmech:chebi-255c99d34c	2026-08-30

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.