amantadine hydrochloride

CHEBI:2619 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A hydrochloride obtained by combining amantadine and hydrochloric acid in equimolar amounts. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:36807 CHEBI:36807

Chemical structure

Computed structure properties
Molecular formula	C10H18N.Cl
Charge	0
Average mass	187.714 Da
Monoisotopic mass	187.11278 Da
Source	ChEBI
InChIKey	WOLHOYHSEKDWQH-UHFFFAOYSA-N

SMILES

[Cl-].[NH3+]C12CC3CC(CC(C3)C1)C2

InChI

InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H

Also called

Symmetrel (BRAND_NAME)— chebi
adamantan-1-aminium chloride (EXACT_SYNONYM)— chebi
1-Adamantanamine hydrochloride (EXACT_SYNONYM)— chebi
1-Adamantylamine hydrochloride (EXACT_SYNONYM)— chebi
1-Aminoadamantane hydrochloride (EXACT_SYNONYM)— chebi
1-Aminoadamantene hydrochlorid (EXACT_SYNONYM)— chebi
Amantadine hydrochloride (EXACT_SYNONYM)— chebi
tricyclo[3.3.1.13,7]decan-1-aminium chloride (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:665-66-7
drugbank:DB00915
gmelin:838463
kegg.compound:C07939
kegg.drug:D00777
reaxys:4198854
wikipedia.en:Amantadine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:22587 CHEBI:22587

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:2619`	amantadine hydrochloride	`antibioticmech:chebi-0e7e4d7c1f`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.