benzatropine mesylate

CHEBI:3049 ·resolve ·ANTIVIRAL ·EXACT SEEDED

The methanesulfonate salt of benzatropine. An acetylcholine receptor antagonist, it is used in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:38037 CHEBI:38037

Chemical structure

Computed structure properties
Molecular formula	C21H26NO.CH3O3S
Charge	0
Average mass	403.544 Da
Monoisotopic mass	403.18173 Da
Source	ChEBI
InChIKey	CPFJLLXFNPCTDW-BWSPSPBFSA-N

SMILES

CS(=O)(=O)[O-].[H][C@@]1(OC(c2ccccc2)c2ccccc2)C[C@]2([H])CC[C@]([H])(C1)[NH+]2C

InChI

InChI=1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;

Also called

(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate (EXACT_SYNONYM)— chebi
(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azoniabicyclo[3.2.1]octane methanesulfonate (EXACT_SYNONYM)— chebi
3-diphenylmethoxytropane mesylate (EXACT_SYNONYM)— chebi
3-diphenylmethoxytropane methanesulfonate (EXACT_SYNONYM)— chebi
3endo-benzhydryloxytropane mesylate (EXACT_SYNONYM)— chebi
3endo-benzhydryloxytropane methanesulphonate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)-1αH,5αH-tropane mesylate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)-1αH,5αH-tropane methanesulfonate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)tropane mesylate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)tropane methanesulfonate (EXACT_SYNONYM)— chebi
benzatropine methanesulfonate (EXACT_SYNONYM)— chebi
benztropine mesilate (EXACT_SYNONYM)— chebi
benztropine mesylate (EXACT_SYNONYM)— chebi
benztropine methanesulfonate (EXACT_SYNONYM)— chebi
tropine benzohydryl ether mesylate (EXACT_SYNONYM)— chebi
tropine benzohydryl ether methanesulphonate (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

beilstein:3826475
cas:132-17-2
drugbank:DB00245
kegg.drug:D00778
patent:US2595405

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:149553 CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:3049`	benzatropine mesylate	`antibioticmech:chebi-f93b4d3d3d`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.