benzatropine mesylate

CHEBI:3049 ·resolve ·ANTIVIRAL ·EXACT SEEDED

The methanesulfonate salt of benzatropine. An acetylcholine receptor antagonist, it is used in the treatment of Parkinson's disease, and to reduce parkinsonism and akathisia side effects of antipsychotic treatments. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:38037

Chemical structure

Computed structure properties
Molecular formula	C21H26NO.CH3O3S
Charge	0
Average mass	403.544 Da
Monoisotopic mass	403.18173 Da
Source	ChEBI
InChIKey	CPFJLLXFNPCTDW-BWSPSPBFSA-N

SMILES

CS(=O)(=O)[O-].[H][C@@]1(OC(c2ccccc2)c2ccccc2)C[C@]2([H])CC[C@]([H])(C1)[NH+]2C

InChI

InChI=1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;

Also called

(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate (EXACT_SYNONYM)— chebi
(3-endo)-3-(diphenylmethoxy)-8-methyl-8-azoniabicyclo[3.2.1]octane methanesulfonate (EXACT_SYNONYM)— chebi
3-diphenylmethoxytropane mesylate (EXACT_SYNONYM)— chebi
3-diphenylmethoxytropane methanesulfonate (EXACT_SYNONYM)— chebi
3endo-benzhydryloxytropane mesylate (EXACT_SYNONYM)— chebi
3endo-benzhydryloxytropane methanesulphonate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)-1αH,5αH-tropane mesylate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)-1αH,5αH-tropane methanesulfonate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)tropane mesylate (EXACT_SYNONYM)— chebi
3α-(diphenylmethoxy)tropane methanesulfonate (EXACT_SYNONYM)— chebi
benzatropine methanesulfonate (EXACT_SYNONYM)— chebi
benztropine mesilate (EXACT_SYNONYM)— chebi
benztropine mesylate (EXACT_SYNONYM)— chebi
benztropine methanesulfonate (EXACT_SYNONYM)— chebi
tropine benzohydryl ether mesylate (EXACT_SYNONYM)— chebi
tropine benzohydryl ether methanesulphonate (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

beilstein:3826475
cas:132-17-2

Drug registries

Identifiers that name a drug rather than a structure. One of these can cover a parent compound, its salts and its stereoisomers, which this corpus keeps as separate records, so it is not an equivalence of structure.

Patents and articles

Documents about this compound. A patent covers a class and an article covers a topic; neither identifies a structure.

patent:US2595405

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

anticoronaviral agent CHEBI:149553

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:3049`	benzatropine mesylate	`antibioticmech:chebi-f93b4d3d3d`	2026-08-30

Mechanism summary

Clinical status: APPROVED

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-09-10 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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