cidofovir anhydrous

CHEBI:3696 ·resolve ·ANTIVIRAL ·EXACT SEEDED

Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:26069 CHEBI:26069
CHEBI:38337 CHEBI:38337

Chemical structure

Computed structure properties
Molecular formula	C8H14N3O6P
Charge	0
Average mass	279.189 Da
Monoisotopic mass	279.06202 Da
Source	ChEBI
InChIKey	VWFCHDSQECPREK-LURJTMIESA-N

SMILES

Nc1ccn(C[C@@H](CO)OCP(=O)(O)O)c(=O)n1

InChI

InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1

Also called

({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid (EXACT_SYNONYM)— chebi
(S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid (EXACT_SYNONYM)— chebi
(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine (EXACT_SYNONYM)— chebi
(S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (EXACT_SYNONYM)— chebi
(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (EXACT_SYNONYM)— chebi
(S)-HPMPC (EXACT_SYNONYM)— chebi
1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (EXACT_SYNONYM)— chebi
1-[(S)-3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (EXACT_SYNONYM)— chebi
CDV (EXACT_SYNONYM)— chebi
Cidofovir (EXACT_SYNONYM)— chebi
Cidofovir anhydrous (EXACT_SYNONYM)— chebi
[(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid (EXACT_SYNONYM)— chebi
cidofovir (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

beilstein:5080484
cas:113852-37-2
drugbank:DB00369
drugcentral:639
kegg.compound:C06909
patent:EP253412
patent:US5142051
wikipedia.en:Cidofovir

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:36044 CHEBI:36044
CHEBI:64946 CHEBI:64946

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:3696`	cidofovir anhydrous	`antibioticmech:chebi-beb9090eff`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.