cinanserin hydrochloride
CHEBI:147284
·resolve ·ANTIVIRAL
·EXACT
SEEDED
The hydrochloride salt of cinanserin. It is an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus (SARS-Cov) and reduces virus replication in vitro. — ChEBI
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C20H24N2OS.HCl |
|---|
| Charge | 0 |
|---|
| Average mass | 376.953 Da |
|---|
| Monoisotopic mass | 376.13761 Da |
|---|
| Source | ChEBI |
|---|
| InChIKey | LXGJPDKYMJJWRB-IERUDJENSA-N |
|---|
SMILES
CN(C)CCCSc1ccccc1NC(=O)/C=C/c1ccccc1.Cl
InChI
InChI=1S/C20H24N2OS.ClH/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17;/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23);1H/b14-13+;
Also called
- (2E)-N-(2-{[3-(dimethylamino)propyl]sulfanyl}phenyl)-3-phenylprop-2-enamide hydrochloride (EXACT_SYNONYM)— chebi
- MAPTC (EXACT_SYNONYM)— chebi
- SQ 10,643 (EXACT_SYNONYM)— chebi
- SQ 10643 (EXACT_SYNONYM)— chebi
- cinanserin HCl (EXACT_SYNONYM)— chebi
Cross-references
Equivalent identifiers for this same structure in other resources.
Activity roles
Every antimicrobial role a source asserts for this compound — the
unreduced evidence behind its antimicrobial_class.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| CHEBI |
CHEBI:147284 |
cinanserin hydrochloride |
antibioticmech:chebi-ea22a1d078 |
2026-08-30 |
Mechanism summary
- Mode of action
- VIRAL_PROTEASE_INHIBITION microbial target — Assigned from ChEBI role CHEBI:147285 (EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor). ChEBI asserts the role on the compound. The role names a target specific to the microbe or virus — see mode_of_action_target_scope. Not a curator's mechanistic review.
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.