costunolide

CHEBI:3900 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A germacranolide with anthelminthic, antiparasitic and antiviral activities. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

CHEBI:33672 CHEBI:33672
CHEBI:73011 CHEBI:73011

Chemical structure

Computed structure properties
Molecular formula	C15H20O2
Charge	0
Average mass	232.323 Da
Monoisotopic mass	232.14633 Da
Source	ChEBI
InChIKey	HRYLQFBHBWLLLL-AHNJNIBGSA-N

SMILES

C=C1C(=O)O[C@@H]2/C=C(\C)CC/C=C(\C)CC[C@@H]12

InChI

InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1

Also called

(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one (EXACT_SYNONYM)— chebi
(+)-costunolide (EXACT_SYNONYM)— chebi
(10S,1R)-3,7-dimethyl-11-methylene-13-oxabicyclo[8.3.0]trideca-2,6-dien-12-one (EXACT_SYNONYM)— chebi
(3aS,6E,10E)-3-methylene-6,10-dimethyl-2,3,3aβ,4,5,8,9,11aα-octahydrocyclodeca[b]furan-2-one (EXACT_SYNONYM)— chebi
(3aS,6E,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one (EXACT_SYNONYM)— chebi
(E,E)-6-alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oic acid gamma-lactone (EXACT_SYNONYM)— chebi
(E,E)-germacra-1(10),4,11(13)-trien-12-oic acid, 6-alpha-hydroxy-gamma-lactone (EXACT_SYNONYM)— chebi
Costunlide (EXACT_SYNONYM)— chebi
Costunolid (EXACT_SYNONYM)— chebi
Costunolide (EXACT_SYNONYM)— chebi
Costus lactone (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

cas:553-21-9
kegg.compound:C09382
knapsack:C00003240
patent:KR20000066932
reaxys:14451
wikipedia.en:Costunolide

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

CHEBI:36044 CHEBI:36044

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:3900`	costunolide	`antibioticmech:chebi-e08ad549d5`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.