AntibioticMech

floxuridine

CHEBI:60761 ·resolve ·ANTIVIRAL ·EXACT SEEDED

A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. — ChEBI

Classification

Strictly broader compounds or drug classes this molecule belongs to.

• CHEBI:19255 CHEBI:19255
• CHEBI:37143 CHEBI:37143
• CHEBI:60783 CHEBI:60783

Chemical structure

Computed structure properties

Molecular formula	C9H11FN2O5
Charge	0
Average mass	246.194 Da
Monoisotopic mass	246.0652 Da
Source	ChEBI
InChIKey	ODKNJVUHOIMIIZ-RRKCRQDMSA-N

SMILES

O=c1nc(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1F

InChI

InChI=1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

Also called

• floxiridina (INN)— chebi
• floxuridinum (INN)— chebi
• 5-fluoro-2'-deoxyuridine (EXACT_SYNONYM)— chebi
• 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil (EXACT_SYNONYM)— chebi
• 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracil (EXACT_SYNONYM)— chebi
• 1beta-D-2'-Deoxyribofuranosyl-5-flurouracil (EXACT_SYNONYM)— chebi
• 2'-Deoxy-5-fluorouridine (EXACT_SYNONYM)— chebi
• 5-Fluoro-2-desoxyuridine (EXACT_SYNONYM)— chebi
• 5-Fluorodeoxyuridine (EXACT_SYNONYM)— chebi
• 5-Fluorouracil 2'-deoxyriboside (EXACT_SYNONYM)— chebi
• 5-Fluorouracil deoxyriboside (EXACT_SYNONYM)— chebi
• 5FDU (EXACT_SYNONYM)— chebi
• Deoxyfluorouridine (EXACT_SYNONYM)— chebi
• FdU (EXACT_SYNONYM)— chebi
• Floxuridin (EXACT_SYNONYM)— chebi
• Floxuridine (EXACT_SYNONYM)— chebi
• Fluorodeoxyuridine (EXACT_SYNONYM)— chebi
• Fluoruridine Deoxyribose (EXACT_SYNONYM)— chebi
• Fluoruridine deoxyribose (EXACT_SYNONYM)— chebi
• beta-5-Fluoro-2'-deoxyuridine (EXACT_SYNONYM)— chebi

Cross-references

Equivalent identifiers for this same structure in other resources.

• cas:50-91-9
• drugbank:DB00322
• drugcentral:1184
• hmdb:HMDB0014467
• kegg.compound:C11736
• kegg.drug:D04197
• lincs.smallmolecule:LSM-5588
• reaxys:90221
• wikipedia.en:Floxuridine

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

• CHEBI:36044 CHEBI:36044

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record

Source	Native ID	Label	Minted CURIE	Version
CHEBI	CHEBI:60761	floxuridine	antibioticmech:chebi-f65d95ec62	2026-08-30

Mechanism summary

Clinical status

APPROVED

Curation history

1. SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Seeded from data/raw/ inventories (CHEBI)

2. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

3. RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

4. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

5. RESEEDED_FROM_SOURCES 2026-08-31 · seed_from_sources

   Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record.