harman

CHEBI:5623 ·resolve ·ANTIVIRAL ·EXACT SEEDED

An indole alkaloid fundamental parent with a structure of 9H-β-carboline carrying a methyl substituent at C-1. It has been isolated from the bark of Sickingia rubra, Symplocus racemosa, Passiflora incarnata, Peganum harmala, Banisteriopsis caapi and Tribulus terrestris, as well as from tobacco smoke. It is a specific, reversible inhibitor of monoamine oxidase A. — ChEBI

Machine-generated and unreviewed. Identity, structure and cross-references come straight from ChEBI's and CARD's own data; no curator has signed off on this record yet.

Classification

Strictly broader compounds or drug classes this molecule belongs to.

Label unavailable CHEBI:38482
Label unavailable CHEBI:38958
Label unavailable CHEBI:61379

Chemical structure

Computed structure properties
Molecular formula	C12H10N2
Charge	0
Average mass	182.226 Da
Monoisotopic mass	182.0844 Da
Source	ChEBI
InChIKey	PSFDQSOCUJVVGF-UHFFFAOYSA-N

SMILES

Cc1nccc2c1nc1ccccc12

InChI

InChI=1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3

Also called

1-methyl-9H-pyrido[3,4-b]indole (EXACT_SYNONYM)— chebi
1-methyl-2-carboline (EXACT_SYNONYM)— chebi
1-methyl-9H-β-carboline (EXACT_SYNONYM)— chebi
1-methyl-β-carboline (EXACT_SYNONYM)— chebi
1-methylnorharman (EXACT_SYNONYM)— chebi
Harman (EXACT_SYNONYM)— chebi
L-methylpyridobindole (EXACT_SYNONYM)— chebi
aribin (EXACT_SYNONYM)— chebi
aribine (EXACT_SYNONYM)— chebi
harmane (EXACT_SYNONYM)— chebi
locuturin (EXACT_SYNONYM)— chebi
locuturine (EXACT_SYNONYM)— chebi
loturine (EXACT_SYNONYM)— chebi
passiflorin (EXACT_SYNONYM)— chebi

Cross-references

Identifiers for this same structure in other resources. An accession that lands on two different structures in this corpus is withheld from both rather than shown here, since it names at most one of them.

Activity roles

Every antimicrobial role a source asserts for this compound — the unreduced evidence behind its antimicrobial_class.

anti-HIV agent CHEBI:64946

Source concepts

Every upstream concept that resolved to this record. The merge is the product: this is what shows ChEBI and CARD are describing the same structure.

Upstream concepts merged into this record
Source	Native ID	Label	Minted CURIE	Version
CHEBI	`CHEBI:5623`	harman	`antibioticmech:chebi-baa72c4a34`	2026-08-30

Curation history

SEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
RESEEDED_FROM_SOURCES 2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories

Provenance

Seeded by scripts/seed_from_sources.py from the committed inventories in data/raw/. View the record (YAML).

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