mefuparib hydrochloride
CHEBI:167899
·resolve ·ANTIVIRAL
·EXACT
SEEDED
The hydrochloride salt of mefuparib. It is a potent poly(ADP-ribose) polymerase inhibitor which exhibits strong anticancer activity and also inhibits SARS-CoV-2 in cell culture. — ChEBI
Machine-generated and unreviewed. Identity, structure and
cross-references come straight from ChEBI's and CARD's own data; no curator has
signed off on this record yet.
Classification
Strictly broader compounds or drug classes this molecule belongs to.
Chemical structure
Computed structure properties
| Molecular formula | C17H15FN2O2.HCl |
|---|
| Charge | 0 |
|---|
| Average mass | 334.778 Da |
|---|
| Monoisotopic mass | 334.08843 Da |
|---|
| Source | ChEBI |
|---|
| InChIKey | GPFWTAVHQKERKY-UHFFFAOYSA-N |
|---|
SMILES
CNCc1ccc(-c2cc3cc(F)cc(C(N)=O)c3o2)cc1.Cl
InChI
InChI=1S/C17H15FN2O2.ClH/c1-20-9-10-2-4-11(5-3-10)15-7-12-6-13(18)8-14(17(19)21)16(12)22-15;/h2-8,20H,9H2,1H3,(H2,19,21);1H
Also called
- 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide hydrochloride (EXACT_SYNONYM)— chebi
- 5-fluoro-2-(4-((methylamino)methyl)phenyl)benzofuran-7-carboxamide hydrochloride (EXACT_SYNONYM)— chebi
- 5-fluoro-2-{4-[(methylamino)methyl]phenyl}-1-benzofuran-7-carboxamide—hydrogen chloride (EXACT_SYNONYM)— chebi
- CVL 218 (EXACT_SYNONYM)— chebi
- CVL-218 (EXACT_SYNONYM)— chebi
- CVL218 (EXACT_SYNONYM)— chebi
- [4-(7-carbamoyl-5-fluoro-1-benzofuran-2-yl)phenyl]-N-methylmethanaminium chloride (EXACT_SYNONYM)— chebi
- mefuparib HCl (EXACT_SYNONYM)— chebi
- mefuparib monohydrochloride (EXACT_SYNONYM)— chebi
Cross-references
Equivalent identifiers for this same structure in other resources.
Activity roles
Every antimicrobial role a source asserts for this compound — the
unreduced evidence behind its antimicrobial_class.
Source concepts
Every upstream concept that resolved to this record. The merge is
the product: this is what shows ChEBI and CARD are describing the same structure.
Upstream concepts merged into this record
| Source | Native ID | Label | Minted CURIE | Version |
|---|
| CHEBI |
CHEBI:167899 |
mefuparib hydrochloride |
antibioticmech:chebi-5fbec2fe8d |
2026-08-30 |
Curation history
-
SEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Seeded from data/raw/ inventories (CHEBI)
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
-
RESEEDED_FROM_SOURCES
2026-08-30 · seed_from_sources
Re-seeded from updated data/raw/ inventories
Provenance
Seeded by scripts/seed_from_sources.py from the committed
inventories in data/raw/.
View the record.